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Distortion of voiced obstruents for differential diagnosis between parkinson's disease and multiple system atrophy

dc.rights.licenseopenen_US
dc.contributor.authorDAOUDI, Khalid
dc.contributor.authorDAS, Biswajit
dc.contributor.authorMILHE DE SAINT VICTOR, Solange
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorSAMIER FOUBERT, Alexandra
dc.contributor.authorPAVY-LE TRAON, Anne
dc.contributor.authorRASCOL, Olivier
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorMEISSNER, Wassilios
IDREF: 113664761
dc.contributor.authorWOISARD, Virginie
dc.contributor.authorINT SPEECH COMMUN, Assoc
dc.date.accessioned2022-10-26T09:19:47Z
dc.date.available2022-10-26T09:19:47Z
dc.date.issued2021-08-30
dc.date.conference2021-08-30
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/170113
dc.description.abstractEnParkinson's disease (PD) and the parkinsonian variant of Multiple System Atrophy (MSA-P) are two neurodegenerative diseases which share similar clinical features, particularly in early disease stages. The differential diagnosis can be thus very challenging. Dysarthria is known to be a frequent and early clinical feature of PD and MSA. It can be thus used as a vehicle to provide a vocal biomarker which could help in the differential diagnosis. In particular, distortion of consonants is known to be a frequent impairment in these diseases. The aim of this study is to investigate distinctive patterns in the distortion of voiced obstruents (plosives and fricatives). It is the first study which attempts to examine such distortions in the French language for the purpose of the differential diagnosis between PD and MSAP (and among the very few studies if we consider all languages). We carry out a perceptual and objective analysis of voiced obstruents extracted from isolated pseudo-words initials. We first show that devoicing is a significant impairment which predominates in MSA-P. We then show that voice onset time (VOT) of voiced plosives (prevoicing duration) can be a complementary feature to improve the accuracy in discrimination between PD and MSA-P.
dc.language.isoENen_US
dc.title.enDistortion of voiced obstruents for differential diagnosis between parkinson's disease and multiple system atrophy
dc.typeCommunication dans un congrès avec actesen_US
dc.identifier.doi10.21437/Interspeech.2021-223en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
bordeaux.page31-35en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.institutionCNRS
bordeaux.conference.titleInterspeech Conferenceen_US
bordeaux.countryczen_US
bordeaux.title.proceedingProc. Interspeech 2021en_US
bordeaux.teamACTIVE_BPHen_US
bordeaux.conference.cityBrnoen_US
bordeaux.peerReviewedouien_US
hal.identifierhal-03830302
hal.version1
hal.date.transferred2022-10-26T09:19:50Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.date=2021-08-30&rft.spage=31-35&rft.epage=31-35&rft.au=DAOUDI,%20Khalid&DAS,%20Biswajit&MILHE%20DE%20SAINT%20VICTOR,%20Solange&SAMIER%20FOUBERT,%20Alexandra&PAVY-LE%20TRAON,%20Anne&rft.genre=proceeding


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