Institut des Maladies Neurodégénératives (IMN) - UMR 5293
L’Institut des Maladies Neurodégénératives (IMN) (UMR 5293) est une Unité Mixte de Recherche associant l’Université de Bordeaux et le CNRS. Il regroupe 11 équipes de recherches fondamentale et préclinique et d’une équipe de Recherche clinique adossée au CHU de Bordeaux. L’IMN associe recherche fondamentale, préclinique et clinique dans le but de :
-Développer de nouvelles approches thérapeutiques des maladies neurodégénératives en facilitant la recherche translationnelle du laboratoire au lit du patient.
-D’accroître sa visibilité et son attractivité dans le champ des neurosciences translationnelles (Maladie de Parkinson et syndromes parkinsoniens atypiques, maladie d’Alzheimer, troubles obsessionnels compulsifs, etc.) et fondamentales (planification, cognition, contrôle moteur, substrats moléculaires de la transmission synaptique) en s’appuyant sur le potentiel de ses équipes et la dynamique mise en place depuis sa création.
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Recent Submissions
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Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.
(Nature Genetics. vol. 56, n° 11, pp. 2333-2344, 2024-11-01)Article de revue -
Adverse childhood experiences and left hippocampal volumetric reductions: A structural magnetic resonance imaging study
(Journal of Psychiatric Research. vol. 180, pp. 183-189, 2024-10-11)Article de revue -
GAP43 Located on Corticostriatal Terminals Restrains Novelty-Induced Hyperactivity in Mice
(Journal of Neuroscience. vol. 44, n° 39, pp. e0701242024, 2024-09-25)Article de revueOpen access -
Are we ready to cure post-stroke cognitive impairment? Many key prerequisites can be achieved quickly and easily
(European Stroke Journal. pp. 23969873241271651, 2024-08-11)Article de revueOpen access -
Explaining the Variability of Alzheimer Disease Fluid Biomarker Concentrations in Memory Clinic Patients Without Dementia
(Neurology. vol. 102, n° 8, pp. e209219, 2024-04-23)Article de revueOpen access -
The pattern of cortical thickness associated with executive dysfunction in MCI and SCC: The MEMENTO cohort
(Revue Neurologique, 2024-06-11)Article de revue -
Trial of Lixisenatide in Early Parkinson’s Disease
(New England Journal of Medicine. vol. 390, n° 13, pp. 1176-1185, 2024-04-04)Article de revue -
Diffusion imaging genomics provides novel insight into early mechanisms of cerebral small vessel disease
(Molecular Psychiatry, 2024-05-29)Article de revueOpen access -
Association of LIfestyle for BRAin health risk score (LIBRA) and genetic susceptibility with incident dementia and cognitive decline
(Alzheimer's & Dementia : the Journal of the Alzheimer's Association. vol. 20, n° 6, pp. 4250-4259, 2024-06-01)Article de revueOpen access -
Genetic variants for head size share genes and pathways with cancer
(Cell Reports Medicine. vol. 5, n° 5, pp. 101529, 2024-05-21)Article de revueOpen access -
Modulate the impact of the drowsiness on the resting state functional connectivity
(Scientific Reports. vol. 14, n° 1, pp. 8652, 2024-04-15)Article de revueOpen access -
Genome sequence analyses identify novel risk loci for multiple system atrophy
(Neuron, 2024-05-02)Article de revueOpen access -
Hypergravity Increases Blood-Brain Barrier Permeability to Fluorescent Dextran and Antisense Oligonucleotide in Mice
(Cells. vol. 12, n° 5, pp. 734, 2023-02-24)Article de revueOpen access -
Addressing unmeasured confounders in cohort studies: Instrumental variable method for a time-fixed exposure on an outcome trajectory
(Biometrical Journal. vol. 66, n° 1, pp. e2200358, 2023-12-14)Article de revueOpen access -
A Pluridisciplinary Tracheostomy Weaning Protocol for Brain-Injured Patients, Outside of the Intensive Care Unit and Without Instrumental Assessment: Results of Pilot Study
(Dysphagia. vol. 39, n° 4, pp. 608-622, 2024-08-01)Article de revueOpen access -
Patient-perceived progression in multiple system atrophy: natural history of quality of life
(Journal of Neurology, Neurosurgery and Psychiatry, 2024-03-07)Article de revueOpen access -
Resective epilepsy surgery and its impact on depression in adults: a systematic review, meta-analysis, and implications for future research
(Journal of Neurology, Neurosurgery and Psychiatry, 2024-03-05)Article de revue -
Effect of a Speaking Valve on Nasal Airflow During Tracheostomy Weaning: A Case Series
(Neurocritical Care, 2024-03-20)Article de revueOpen access -
Disease Progression in Multiple System Atrophy: The Value of Clinical Cohorts with Long Follow-Up
(Movement disorders. vol. 38, n° 8, pp. 1567-1569, 2023-08-01)Article de revueOpen access -
Lifespan neurodegeneration of the human brain in multiple sclerosis
(Human Brain Mapping. vol. 44, n° 17, pp. 5602-5611, 2023-03-14)Article de revueOpen access
Statistics
Collection General Statistics
Typology History
2020 | 2021 | 2022 | 2023 | 2024 | |
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Actes de congrès/Proceedings | 0 | 0 | 0 | 0 | 0 |
Article de blog scientifique | 0 | 0 | 0 | 0 | 0 |
Article de revue | 5 | 12 | 12 | 20 | 20 |
Autre document | 0 | 0 | 0 | 0 | 0 |
Brevet | 0 | 0 | 0 | 0 | 0 |
Chapitre d'ouvrage | 0 | 0 | 0 | 0 | 0 |
Communication dans un congrès | 0 | 0 | 0 | 0 | 0 |
Document de travail - Pré-publication | 0 | 0 | 0 | 1 | 0 |
HDR | 0 | 0 | 0 | 0 | 0 |
Notice d'encyclopédie ou de dictionnaire | 0 | 0 | 0 | 0 | 0 |
N°spécial de revue/special issue | 0 | 0 | 0 | 0 | 0 |
Ouvrage | 0 | 0 | 0 | 0 | 0 |
Poster | 0 | 0 | 0 | 0 | 0 |
Rapport | 0 | 0 | 0 | 0 | 0 |
Thèse d'exercice | 0 | 0 | 0 | 0 | 0 |
Thèses de doctorat | 3 | 4 | 2 | 0 | 0 |
Traduction | 0 | 0 | 0 | 0 | 0 |