Institut des Maladies Neurodégénératives (IMN)

L’Institut des Maladies Neurodégénératives (IMN) (UMR 5293) est une Unité Mixte de Recherche associant l’Université de Bordeaux et le CNRS. Il regroupe 11 équipes de recherches fondamentale et préclinique et d’une équipe de Recherche clinique adossée au CHU de Bordeaux. L’IMN associe recherche fondamentale, préclinique et clinique dans le but de :

-Développer de nouvelles approches thérapeutiques des maladies neurodégénératives en facilitant la recherche translationnelle du laboratoire au lit du patient.

-D’accroître sa visibilité et son attractivité dans le champ des neurosciences translationnelles (Maladie de Parkinson et syndromes parkinsoniens atypiques, maladie d’Alzheimer, troubles obsessionnels compulsifs, etc.) et fondamentales (planification, cognition, contrôle moteur, substrats moléculaires de la transmission synaptique) en s’appuyant sur le potentiel de ses équipes et la dynamique mise en place depuis sa création.

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Institut des Maladies Neurodégénératives (IMN) - UMR 5293

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Recent Submissions

Peripheral neuropathy and livedoid vasculopathy

Validity and Performance of Blood Biomarkers for Alzheimer Disease to Predict Dementia Risk in a Large Clinic-Based Cohort

Switch of serotonergic descending inhibition into facilitation by a spinal chloride imbalance in neuropathic pain

The Unified Multiple System Atrophy Rating Scale: Status, Critique, and Recommendations

Association of a MIND Diet with Brain Structure and Dementia in a French Population

Alterations in electrochemical skin conductance as a marker of autonomic dysfunction in multiple system atrophy

Distortion of voiced obstruents for differential diagnosis between parkinson's disease and multiple system atrophy

Hippocampal-amygdalo-ventricular atrophy score: Alzheimer disease detection using normative and pathological lifespan models.

Neurofilament light levels predict clinical progression and death in multiple system atrophy

A New Rise of Non-Human Primate Models of Synucleinopathies

Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques

Macros to Quantify Exosome Release and Autophagy at the Neuromuscular Junction of Drosophila Melanogaster

PLGA-Based Nanoparticles for Neuroprotective Drug Delivery in Neurodegenerative Diseases

A Disynaptic Circuit in the Globus Pallidus Controls Locomotion Inhibition

Complement C3 mediates early hippocampal neurodegeneration and memory impairment in experimental multiple sclerosis.

Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.

Diagnostic value of cerebrospinal fluid alpha-synuclein seed quantification in synucleinopathies

Ambulatory blood pressure and drug treatment for orthostatic hypotension as predictors of mortality in patients with Multiple System Atrophy

Fish Intake and MRI Burden of Cerebrovascular Disease in Older Adults

A Biological Index to Screen Multi-Micronutrient Deficiencies Associated with the Risk to Develop Dementia in Older Persons from the Community

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Institut des Maladies Neurodégénératives (IMN) - UMR 5293

Browse by

Recent Submissions

Peripheral neuropathy and livedoid vasculopathy ﻿

Validity and Performance of Blood Biomarkers for Alzheimer Disease to Predict Dementia Risk in a Large Clinic-Based Cohort ﻿

Switch of serotonergic descending inhibition into facilitation by a spinal chloride imbalance in neuropathic pain ﻿

The Unified Multiple System Atrophy Rating Scale: Status, Critique, and Recommendations ﻿

Association of a MIND Diet with Brain Structure and Dementia in a French Population ﻿

Alterations in electrochemical skin conductance as a marker of autonomic dysfunction in multiple system atrophy ﻿

Distortion of voiced obstruents for differential diagnosis between parkinson's disease and multiple system atrophy ﻿

Hippocampal-amygdalo-ventricular atrophy score: Alzheimer disease detection using normative and pathological lifespan models. ﻿

Neurofilament light levels predict clinical progression and death in multiple system atrophy ﻿

A New Rise of Non-Human Primate Models of Synucleinopathies ﻿

Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques ﻿

Macros to Quantify Exosome Release and Autophagy at the Neuromuscular Junction of Drosophila Melanogaster ﻿

PLGA-Based Nanoparticles for Neuroprotective Drug Delivery in Neurodegenerative Diseases ﻿

A Disynaptic Circuit in the Globus Pallidus Controls Locomotion Inhibition ﻿

Complement C3 mediates early hippocampal neurodegeneration and memory impairment in experimental multiple sclerosis. ﻿

Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate. ﻿

Diagnostic value of cerebrospinal fluid alpha-synuclein seed quantification in synucleinopathies ﻿

Ambulatory blood pressure and drug treatment for orthostatic hypotension as predictors of mortality in patients with Multiple System Atrophy ﻿

Fish Intake and MRI Burden of Cerebrovascular Disease in Older Adults ﻿

A Biological Index to Screen Multi-Micronutrient Deficiencies Associated with the Risk to Develop Dementia in Older Persons from the Community ﻿