Institut des Maladies Neurodégénératives (IMN)

L’Institut des Maladies Neurodégénératives (IMN) (UMR 5293) est une Unité Mixte de Recherche associant l’Université de Bordeaux et le CNRS. Il regroupe 11 équipes de recherches fondamentale et préclinique et d’une équipe de Recherche clinique adossée au CHU de Bordeaux. L’IMN associe recherche fondamentale, préclinique et clinique dans le but de :

-Développer de nouvelles approches thérapeutiques des maladies neurodégénératives en facilitant la recherche translationnelle du laboratoire au lit du patient.

-D’accroître sa visibilité et son attractivité dans le champ des neurosciences translationnelles (Maladie de Parkinson et syndromes parkinsoniens atypiques, maladie d’Alzheimer, troubles obsessionnels compulsifs, etc.) et fondamentales (planification, cognition, contrôle moteur, substrats moléculaires de la transmission synaptique) en s’appuyant sur le potentiel de ses équipes et la dynamique mise en place depuis sa création.

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Institut des Maladies Neurodégénératives (IMN) - UMR 5293

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Dépôts récents

Genetic labeling of embryonically-born dentate granule neurons in young mice using the PenkCre mouse line

Vulnerability of Thalamic Nuclei at CSF Interface During the Entire Course of Multiple Sclerosis

Resting state connectivity patterns associated with trait anxiety in adolescence

Statistical harmonization of versions of measures across studies using external data: Self-rated health and self-rated memory

Amantadine use in the French prospective NS-Park cohort

SHIVA-CMB: a deep-learning-based robust cerebral microbleed segmentation tool trained on multi-source T2*GRE- and susceptibility-weighted MRI

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.

Adverse childhood experiences and left hippocampal volumetric reductions: A structural magnetic resonance imaging study

GAP43 Located on Corticostriatal Terminals Restrains Novelty-Induced Hyperactivity in Mice

Are we ready to cure post-stroke cognitive impairment? Many key prerequisites can be achieved quickly and easily

Explaining the Variability of Alzheimer Disease Fluid Biomarker Concentrations in Memory Clinic Patients Without Dementia

The pattern of cortical thickness associated with executive dysfunction in MCI and SCC: The MEMENTO cohort

Trial of Lixisenatide in Early Parkinson’s Disease

Diffusion imaging genomics provides novel insight into early mechanisms of cerebral small vessel disease

Association of LIfestyle for BRAin health risk score (LIBRA) and genetic susceptibility with incident dementia and cognitive decline

Genetic variants for head size share genes and pathways with cancer

Modulate the impact of the drowsiness on the resting state functional connectivity

Genome sequence analyses identify novel risk loci for multiple system atrophy

Hypergravity Increases Blood-Brain Barrier Permeability to Fluorescent Dextran and Antisense Oligonucleotide in Mice

Addressing unmeasured confounders in cohort studies: Instrumental variable method for a time-fixed exposure on an outcome trajectory

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Dépôs récents

Institut des Maladies Neurodégénératives (IMN) - UMR 5293

Parcourir par

Dépôts récents

Genetic labeling of embryonically-born dentate granule neurons in young mice using the PenkCre mouse line ﻿

Vulnerability of Thalamic Nuclei at CSF Interface During the Entire Course of Multiple Sclerosis ﻿

Resting state connectivity patterns associated with trait anxiety in adolescence ﻿

Statistical harmonization of versions of measures across studies using external data: Self-rated health and self-rated memory ﻿

Amantadine use in the French prospective NS-Park cohort ﻿

SHIVA-CMB: a deep-learning-based robust cerebral microbleed segmentation tool trained on multi-source T2*GRE- and susceptibility-weighted MRI ﻿

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries. ﻿

Adverse childhood experiences and left hippocampal volumetric reductions: A structural magnetic resonance imaging study ﻿

GAP43 Located on Corticostriatal Terminals Restrains Novelty-Induced Hyperactivity in Mice ﻿

Are we ready to cure post-stroke cognitive impairment? Many key prerequisites can be achieved quickly and easily ﻿

Explaining the Variability of Alzheimer Disease Fluid Biomarker Concentrations in Memory Clinic Patients Without Dementia ﻿

The pattern of cortical thickness associated with executive dysfunction in MCI and SCC: The MEMENTO cohort ﻿

Trial of Lixisenatide in Early Parkinson’s Disease ﻿

Diffusion imaging genomics provides novel insight into early mechanisms of cerebral small vessel disease ﻿

Association of LIfestyle for BRAin health risk score (LIBRA) and genetic susceptibility with incident dementia and cognitive decline ﻿

Genetic variants for head size share genes and pathways with cancer ﻿

Modulate the impact of the drowsiness on the resting state functional connectivity ﻿

Genome sequence analyses identify novel risk loci for multiple system atrophy ﻿

Hypergravity Increases Blood-Brain Barrier Permeability to Fluorescent Dextran and Antisense Oligonucleotide in Mice ﻿

Addressing unmeasured confounders in cohort studies: Instrumental variable method for a time-fixed exposure on an outcome trajectory ﻿