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Rat feeding trials: A comprehensive assessment of contaminants in both genetically modified maize and resulting pellets.

hal.structure.identifierUnité de recherche Mycologie et Sécurité des Aliments [MycSA]
dc.contributor.authorCHÉREAU, Sylvain
hal.structure.identifierReproduction et développement des plantes [RDP]
dc.contributor.authorROGOWSKY, Peter
hal.structure.identifierToxAlim [ToxAlim]
dc.contributor.authorLAPORTE, Bérengère
hal.structure.identifierInstitut National de la Santé et de la Recherche Médicale [INSERM]
hal.structure.identifierToxicité environnementale, cibles thérapeutiques, signalisation cellulaire [T3S - UMR_S 1124]
dc.contributor.authorCOUMOUL, X.
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorMOING, Annick
hal.structure.identifierPrévention et promotion de la cancérogénèse par les aliments [ToxAlim-PPCA]
dc.contributor.authorPRIYMENKO, Nathalie
hal.structure.identifierUniversity of Veterinary Medicine Hannover
dc.contributor.authorSTEINBERG, P.
hal.structure.identifierJulius Kühn-Institut [JKI]
dc.contributor.authorWILHELM, R.
hal.structure.identifierJulius Kühn-Institut [JKI]
dc.contributor.authorSCHIEMANN, J.
hal.structure.identifierToxAlim [ToxAlim]
dc.contributor.authorSALLES, Bernard
hal.structure.identifierUnité de recherche Mycologie et Sécurité des Aliments [MycSA]
dc.contributor.authorRICHARD-FORGET, Florence
dc.date.issued2018
dc.identifier.issn0278-6915
dc.description.abstractEnWe analyzed a comprehensive set of contaminants in MON810 and NK603 genetically modified (GM) maize, and their non-GM counterparts, used in a rat feeding study (the GMO90 + project). Both the maize grains and the manufactured pellets were characterized. Only minor differences in contaminant levels between GM and corresponding non-GM harvests were evidenced. Fumonisin and deoxynivalenol mycotoxins were the pollutants present in the highest amounts, with concentrations that were however largely below acceptance reference values. Our data reporting slightly higher levels of fumonisin in MON810 compared to its non-GM counterpart corroborate the lower susceptibility of insect resistant Bt maize to fumonisin-producing fungi. Traces of glyphosate (0.016 mg/kg) were evidenced in grains from NK603 treated crops. Regarding the pellets, analysis of more than 650 potentially toxic substances revealed low amounts of various mycotoxins, pesticides and heavy metals. Concentrations of contaminants quantified in the pellets were however far below the maximum level of residues values set by regulatory agencies, and no substantial differences in contaminants between GM and non-GM pellets were observed. Moreover, when comparing the contamination status of grains and pellets, we demonstrate yet again that characterizing the grains is actually not sufficient to foresee the quality of the produced pellets.
dc.language.isoen
dc.publisherElsevier
dc.subjectMycotoxins
dc.subjectPesticides
dc.subject.enGM maize
dc.subject.enGM pellets
dc.subject.enHeavy metals
dc.title.enRat feeding trials: A comprehensive assessment of contaminants in both genetically modified maize and resulting pellets.
dc.typeArticle de revue
dc.identifier.doi10.1016/j.fct.2018.09.049
dc.subject.halSciences du Vivant [q-bio]/Toxicologie/Toxicologie végétale et mycotoxicologie
dc.subject.halSciences du Vivant [q-bio]/Biologie animale
dc.subject.halSciences du Vivant [q-bio]/Biologie végétale
bordeaux.journalFood and Chemical Toxicology
bordeaux.page573-582
bordeaux.volume121
bordeaux.peerReviewedoui
hal.identifierhal-02623829
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-02623829v1
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