Afficher la notice abrégée

Genome sequence of the Drosophila melanogaster male-killing Spiroplasma strain MSRO endosymbiont.

hal.structure.identifierGlobal Health Institute
dc.contributor.authorPAREDES, Juan C.
hal.structure.identifierGlobal Health Institute
dc.contributor.authorHERREN, Jeremy K.
hal.structure.identifierGlobal Health Institute
dc.contributor.authorSCHÜPFER, Fanny
hal.structure.identifierCenter for Integrative Genomics - Institute of Bioinformatics, Génopode [CIG]
dc.contributor.authorMARIN, Ray
hal.structure.identifierUniversité de Bordeaux [UB]
dc.contributor.authorCLAVEROL, Stéphane
hal.structure.identifierAcademia Sinica
dc.contributor.authorKUO, Chih-Horng
hal.structure.identifierGlobal Health Institute
dc.contributor.authorLEMAITRE, Bruno
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorBEVEN, Laure
dc.date.issued2015
dc.identifier.issn2161-2129
dc.description.abstractEnMost insect species, including important disease vectors and crop pests, harbor vertically transmitted endosymbiotic bacteria. These endosymbionts play key roles in their hosts' fitness, including protecting them against natural enemies and manipulating their reproduction in ways that increase the frequency of symbiont infection. Little is known about the molecular mechanisms that underlie these processes. Here, we provide the first genome draft of a vertically transmitted male-killing Spiroplasma bacterium, the S. poulsonii MSRO strain harbored by D. melanogaster. Analysis of the S. poulsonii genome was complemented by proteomics and ex vivo metabolic experiments. Our results indicate that S. poulsonii has reduced metabolic capabilities and expresses divergent membrane lipoproteins and potential virulence factors that likely participate in Spiroplasma-host interactions. This work fills a gap in our knowledge of insect endosymbionts and provides tools with which to decipher the interaction between Spiroplasma bacteria and their well-characterized host D. melanogaster, which is emerging as a model of endosymbiosis.
dc.language.isoen
dc.publisherAmerican Society for Microbiology
dc.rights.urihttp://creativecommons.org/licenses/by/
dc.title.enGenome sequence of the Drosophila melanogaster male-killing Spiroplasma strain MSRO endosymbiont.
dc.typeArticle de revue
dc.identifier.doi10.1128/mBio.02437-14
dc.subject.halSciences du Vivant [q-bio]/Sciences agricoles
dc.subject.halSciences du Vivant [q-bio]/Microbiologie et Parasitologie
bordeaux.journalmBio
bordeaux.volume6
bordeaux.issue2
bordeaux.peerReviewedoui
hal.identifierhal-02632623
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-02632623v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=mBio&rft.date=2015&rft.volume=6&rft.issue=2&rft.eissn=2161-2129&rft.issn=2161-2129&rft.au=PAREDES,%20Juan%20C.&HERREN,%20Jeremy%20K.&SCH%C3%9CPFER,%20Fanny&MARIN,%20Ray&CLAVEROL,%20St%C3%A9phane&rft.genre=article


Fichier(s) constituant ce document

FichiersTailleFormatVue

Il n'y a pas de fichiers associés à ce document.

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée