Study of the interaction of β-cyclodextrin with phospholipid monolayers by surface pressure measurements and fluorescence microscopy
hal.structure.identifier | Centre de physique moléculaire optique et hertzienne [CPMOH] | |
dc.contributor.author | GRAUBY-HEYWANG, Christine | |
hal.structure.identifier | Centre de physique moléculaire optique et hertzienne [CPMOH] | |
dc.contributor.author | TURLET, Jean-Marie | |
dc.date.created | 2007-10-26 | |
dc.date.issued | 2008-06-01 | |
dc.identifier.issn | 0021-9797 | |
dc.description.abstractEn | The interaction of β-cyclodextrin (β-CD) with different lipids has been studied, using Langmuir monolayers kept at constant surface pressure or constant spreading surface. Results show that β-CD, injected beneath the monolayer, is able to desorb unsaturated palmitoyloleoylphosphatidylcholine (POPC) and sphingomyelin (SM) under specific experimental conditions. In this last case, SM monolayers, labeled with the fluorescent NBD-PC probe, were also observed by fluorescence microscopy, before and after β-CD injection. Images show that SM monolayers are more homogeneous after β-CD injection, because of the lipid desorption. At last, it seems that lipid desorption occurs only in a restricted surface pressure range, depending on the lipid. | |
dc.language.iso | en | |
dc.publisher | Elsevier | |
dc.subject.en | β-Cyclodextrin | |
dc.subject.en | Phospholipid | |
dc.subject.en | Monolayer | |
dc.subject.en | Desorption | |
dc.subject.en | Surface pressure measurements | |
dc.subject.en | Fluorescence microscopy | |
dc.title.en | Study of the interaction of β-cyclodextrin with phospholipid monolayers by surface pressure measurements and fluorescence microscopy | |
dc.type | Article de revue | |
dc.identifier.doi | 10.1016/j.jcis.2008.03.025 | |
bordeaux.journal | Journal of Colloid and Interface Science | |
bordeaux.page | 73-78 | |
bordeaux.volume | 322 | |
bordeaux.issue | 1 | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-00747240 | |
hal.version | 1 | |
hal.popular | non | |
hal.audience | Internationale | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-00747240v1 | |
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