GRAUBY-HEYWANG, Christine; TURLET, Jean-Marie

doi:10.1016/j.jcis.2008.03.025

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GRAUBY-HEYWANG, Christine
Centre de physique moléculaire optique et hertzienne [CPMOH]

TURLET, Jean-Marie
Centre de physique moléculaire optique et hertzienne [CPMOH]

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Journal of Colloid and Interface Science. 2008-06-01, vol. 322, n° 1, p. 73-78

Elsevier

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The interaction of β-cyclodextrin (β-CD) with different lipids has been studied, using Langmuir monolayers kept at constant surface pressure or constant spreading surface. Results show that β-CD, injected beneath the monolayer, is able to desorb unsaturated palmitoyloleoylphosphatidylcholine (POPC) and sphingomyelin (SM) under specific experimental conditions. In this last case, SM monolayers, labeled with the fluorescent NBD-PC probe, were also observed by fluorescence microscopy, before and after β-CD injection. Images show that SM monolayers are more homogeneous after β-CD injection, because of the lipid desorption. At last, it seems that lipid desorption occurs only in a restricted surface pressure range, depending on the lipid.< Leer menos

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β-Cyclodextrin

Phospholipid

Monolayer

Desorption

Surface pressure measurements

Fluorescence microscopy

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Study of the interaction of β-cyclodextrin with phospholipid monolayers by surface pressure measurements and fluorescence microscopy

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