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Study of in vitro antimicrobial and antiproliferative activities of selected Saharan plants

hal.structure.identifierUniversity of Medicine and Pharmacy
dc.contributor.authorPALICI, Ionut F.
hal.structure.identifierUniversity of Szeged [Szeged]
dc.contributor.authorLIKTOR-BUSA, Erika
hal.structure.identifierUniversity of Szeged [Szeged]
dc.contributor.authorZUPKÓ, István
hal.structure.identifierBiodiversité, Gènes & Communautés [BioGeCo]
dc.contributor.authorTOUZARD, Blaise
hal.structure.identifierUniversité de Sfax
dc.contributor.authorCHAIEB, Mohamed
hal.structure.identifierUniversity of Szeged [Szeged]
dc.contributor.authorURBÁN, Edit
hal.structure.identifierUniversity of Szeged [Szeged]
dc.contributor.authorHOHMANN, Judit
dc.date.issued2015
dc.identifier.issn0236-5383
dc.description.abstractEnThe aim of the present study was the evaluation of the antimicrobial and antiproliferative activities of selected Saharan species, which are applied in the traditional medicine but not studied thoroughly from chemical and pharmacological point of view. The studied plants, namely Anthyllis henoniana, Centropodia forskalii, Cornulaca monacantha, Ephedra alata var. alenda, Euphorbia guyoniana, Helianthemum confertum, Henophyton deserti, Moltkiopsis ciliata and Spartidium saharae were collected from remote areas of North Africa, especially from the Tunisian region of Sahara. After drying and applying the appropriate extraction methods, the plant extracts were tested in antimicrobial screening assay, performed on 19 Gram-positive and -negative strains of microbes. The inhibition zones produced by plant extracts were determined by disc-diffusion method. Remarkable antibacterial activities were exhibited by extracts of Ephedra alata var. alenda and Helianthemum confertum against B. subtilis, M. catarrhalis and methicillin-resistant and non-resistant S. aureus. Minimum inhibitory concentrations of these two species were also determined. Antiproliferative effects of the extracts were evaluated against 4 human adherent cell lines (HeLa, A431, A2780 and MCF7). Notable cell growth inhibition was found for extract of Helianthemum confertum and Euphorbia guyoniana. Our results provided data for selection of some plant species for further detailed pharmacological and phytochemical examinations.
dc.language.isoen
dc.publisherAkadémiai Kiadó
dc.subjectEphedra alata var. alenda
dc.subjectSaharan plants
dc.subject.enHelianthemum confertum
dc.subject.enantibacterial activity
dc.subject.enantiproliferative activity
dc.title.enStudy of in vitro antimicrobial and antiproliferative activities of selected Saharan plants
dc.typeArticle de revue
dc.identifier.doi10.1556/018.66.2015.4.3
dc.subject.halSciences du Vivant [q-bio]
bordeaux.journalActa Biologica Hungarica
bordeaux.page385-394
bordeaux.volume66
bordeaux.issue4
bordeaux.peerReviewedoui
hal.identifierhal-02640739
hal.version1
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-02640739v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Acta%20Biologica%20Hungarica&rft.date=2015&rft.volume=66&rft.issue=4&rft.spage=385-394&rft.epage=385-394&rft.eissn=0236-5383&rft.issn=0236-5383&rft.au=PALICI,%20Ionut%20F.&LIKTOR-BUSA,%20Erika&ZUPK%C3%93,%20Istv%C3%A1n&TOUZARD,%20Blaise&CHAIEB,%20Mohamed&rft.genre=article


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