| hal.structure.identifier | Laboratoire des Interactions Virus-Hôtes [Cayenne, Guyane Française] | |
| hal.structure.identifier | Institut Pasteur de la Guyane | |
| dc.contributor.author | TIRERA, Sourakhata | |
| hal.structure.identifier | Laboratoire des Interactions Virus-Hôtes [Cayenne, Guyane Française] | |
| hal.structure.identifier | Institut Pasteur de la Guyane | |
| dc.contributor.author | DE THOISY, Benoit | |
| hal.structure.identifier | Laboratoire des Interactions Virus-Hôtes [Cayenne, Guyane Française] | |
| hal.structure.identifier | Institut Pasteur de la Guyane | |
| dc.contributor.author | DONATO, Damien | |
| hal.structure.identifier | Institut Pasteur [Paris] [IP] | |
| dc.contributor.author | BOUCHIER, Christiane | |
| hal.structure.identifier | Laboratoire des Interactions Virus-Hôtes [Cayenne, Guyane Française] | |
| hal.structure.identifier | Institut Pasteur de la Guyane | |
| hal.structure.identifier | Institut Pasteur du Laos | |
| dc.contributor.author | LACOSTE, Vincent | |
| hal.structure.identifier | Biodiversité, Gènes & Communautés [BioGeCo] | |
| hal.structure.identifier | Pleiade, from patterns to models in computational biodiversity and biotechnology [PLEIADE] | |
| dc.contributor.author | FRANC, Alain | |
| hal.structure.identifier | Laboratoire des Interactions Virus-Hôtes [Cayenne, Guyane Française] | |
| hal.structure.identifier | Institut Pasteur de la Guyane | |
| dc.contributor.author | LAVERGNE, Anne | |
| dc.date.accessioned | 2022-10-12T12:01:49Z | |
| dc.date.available | 2022-10-12T12:01:49Z | |
| dc.date.issued | 2021 | |
| dc.identifier.issn | 1999-4915 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/155660 | |
| dc.description.abstractEn | Rodents are important reservoirs of numerous viruses, some of which have significant impacts on public health. Ecosystem disturbances and decreased host species richness have been associated with the emergence of zoonotic diseases. In this study, we aimed at (a) characterizing the viral diversity in seven neotropical rodent species living in four types of habitats and (b) exploring how the extent of environmental disturbance influences this diversity. Through a metagenomic approach, we identified 77,767 viral sequences from spleen, kidney, and serum samples. These viral sequences were attributed to 27 viral families known to infect vertebrates, invertebrates, plants, and amoeba. Viral diversities were greater in pristine habitats compared with disturbed ones, and lowest in peri-urban areas. High viral richness was observed in savannah areas. Differences in these diversities were explained by rare viruses that were generally more frequent in pristine forest and savannah habitats. Moreover, changes in the ecology and behavior of rodent hosts, in a given habitat, such as modifications to the diet in disturbed vs. pristine forests, are major determinants of viral composition. Lastly, the phylogenetic relationships of four vertebrate-related viral families (Polyomaviridae, Flaviviridae, Togaviridae, and Phenuiviridae) highlighted the wide diversity of these viral families, and in some cases, a potential risk of transmission to humans. All these findings provide significant insights into the diversity of rodent viruses in Amazonia, and emphasize that habitats and the host’s dietary ecology may drive viral diversity. Linking viral richness and abundance to the ecology of their hosts and their responses to habitat disturbance could be the starting point for a better understanding of viral emergence and for future management of ecosystems. | |
| dc.description.sponsorship | CEnter of the study of Biodiversity in Amazonia - ANR-10-LABX-0025 | |
| dc.description.sponsorship | Organisation et montée en puissance d'une Infrastructure Nationale de Génomique - ANR-10-INBS-0009 | |
| dc.language.iso | en | |
| dc.publisher | MDPI | |
| dc.rights.uri | http://creativecommons.org/licenses/by/ | |
| dc.subject.en | virome | |
| dc.subject.en | alpha diversity | |
| dc.subject.en | rodents | |
| dc.subject.en | Amazonia | |
| dc.subject.en | viral ecology | |
| dc.subject.en | viral phylogenies | |
| dc.title.en | The Influence of Habitat on Viral Diversity in Neotropical Rodent Hosts | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.3390/v13091690 | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Microbiologie et Parasitologie/Virologie | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Biodiversité | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Ecologie, Environnement/Interactions entre organismes | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Ecologie, Environnement/Ecosystèmes | |
| bordeaux.journal | Viruses | |
| bordeaux.volume | 13 | |
| bordeaux.hal.laboratories | BioGeCo (Biodiversité Gènes & Communautés) - UMR 1202 | * |
| bordeaux.issue | 9 | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.institution | INRAE | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-03690912 | |
| hal.version | 1 | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-03690912v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Viruses&rft.date=2021&rft.volume=13&rft.issue=9&rft.eissn=1999-4915&rft.issn=1999-4915&rft.au=TIRERA,%20Sourakhata&DE%20THOISY,%20Benoit&DONATO,%20Damien&BOUCHIER,%20Christiane&LACOSTE,%20Vincent&rft.genre=article | |
