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Impact of dietary cadmium sulphide nanoparticles on Danio rerio zebrafish at very low contamination pressure.

hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorLADHAR, Chiraz
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorGEFFROY, Benjamin
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorCAMBIER, Sébastien
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorTRÉGUER-DELAPIERRE, Mona
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorDURAND, Étienne
hal.structure.identifierInstitut de biochimie et génétique cellulaires [IBGC]
dc.contributor.authorBRÈTHES, Daniel
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorBOURDINEAUD, Jean-Paul
dc.date.issued2014
dc.identifier.issn1743-5390
dc.description.abstractEn: Abstract To address the impact of cadmium sulphide nanoparticles (CdSNPs) of two different sizes (8 and 50 nm), Danio rerio zebrafish were dietary exposed to very low doses: 100 or 40 ng CdSNPs/day/g body weight for 36 or 60 days, respectively. The results obtained using RAPD-PCR genotoxicity test showed genomic alteration since the number of hybridisation sites of the RAPD probes was significantly modified after CdSNPs exposure. In addition, selected stress response genes were either repressed or upregulated in tissues of CdSNPs-exposed fish. Mitochondrial dysfunction was also caused by the presence of CdSNPs in food. Cadmium accumulation in fish tissues (brain and muscles) could only be observed after 60 days of exposure. CdSNPs toxicity was dependent on their size and concentration.
dc.language.isoen
dc.publisherTaylor & Francis
dc.title.enImpact of dietary cadmium sulphide nanoparticles on Danio rerio zebrafish at very low contamination pressure.
dc.typeArticle de revue
dc.identifier.doi10.3109/17435390.2013.822116
dc.subject.halSciences du Vivant [q-bio]/Biologie cellulaire
bordeaux.journalNanotoxicology
bordeaux.page676-685
bordeaux.volume8
bordeaux.issue6
bordeaux.peerReviewedoui
hal.identifierhal-00905839
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00905839v1
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