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Loading and release of internally self-assembled emulsions embedded in a magnetic hydrogel

hal.structure.identifierChimie, Structures et Propriétés de Biomatériaux et d'Agents Thérapeutiques [CSPBAT]
dc.contributor.authorMILO SEVIC, Irena
hal.structure.identifierChimie, Structures et Propriétés de Biomatériaux et d'Agents Thérapeutiques [CSPBAT]
dc.contributor.authorGUILLOT, Samuel
hal.structure.identifierVinča Institute of Nuclear Sciences
dc.contributor.authorTADIC, Marin
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorDUTTINE, Mathieu
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorDUGUET, Etienne
hal.structure.identifierInstitute of Condensed Matter Physics [Lausanne]
dc.contributor.authorPIERZCHALA, Katarzyna
hal.structure.identifierInstitute of Condensed Matter Physics [Lausanne]
dc.contributor.authorSIENKIEWICZ, Andrzej
hal.structure.identifierInstitute of Condensed Matter Physics [Lausanne]
dc.contributor.authorFORR O, L Aszl O
hal.structure.identifierChimie, Structures et Propriétés de Biomatériaux et d'Agents Thérapeutiques [CSPBAT]
hal.structure.identifierInstitut de minéralogie et de physique des milieux condensés [IMPMC]
dc.contributor.authorSABOUNGI, Marie-Louise
dc.date.issued2014
dc.identifier.issn0003-6951
dc.description.abstractEnWe have investigated drug loading and release from thermosensitive gel emulsions with external triggering by an alternating magnetic field (AMF) for on-demand drug delivery. Superparamagnetic iron oxide nanoparticles dispersed in gel emulsions were used to study the loading and release capabilities, with the stable nitroxide radical 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) serving as the model drug. AMF activation gave similar results to temperature activation in a water bath at 37 C, showing that the principal effect of the AMF is a temperature increase without burst release. These results suggest that the system could play an important role in the development of advanced drug delivery.
dc.language.isoen
dc.publisherAmerican Institute of Physics
dc.title.enLoading and release of internally self-assembled emulsions embedded in a magnetic hydrogel
dc.typeArticle de revue
dc.identifier.doi10.1063/1.4862811
dc.subject.halChimie/Polymères
dc.subject.halPhysique [physics]/Matière Condensée [cond-mat]/Matière Molle [cond-mat.soft]
dc.subject.halSciences du Vivant [q-bio]/Sciences pharmaceutiques/Pharmacologie
bordeaux.journalApplied Physics Letters
bordeaux.page043701
bordeaux.volume104
bordeaux.issue4
bordeaux.peerReviewedoui
hal.identifierhal-00939100
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00939100v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Applied%20Physics%20Letters&rft.date=2014&rft.volume=104&rft.issue=4&rft.spage=043701&rft.epage=043701&rft.eissn=0003-6951&rft.issn=0003-6951&rft.au=MILO%20SEVIC,%20Irena&GUILLOT,%20Samuel&TADIC,%20Marin&DUTTINE,%20Mathieu&DUGUET,%20Etienne&rft.genre=article


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