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Pickering emulsion as template for porous bioceramics in the perspective of bone regeneration

dc.rights.licenseopenen_US
dc.contributor.authorPASCAUD, K.
hal.structure.identifierCentre de Recherche Paul Pascal [CRPP]
dc.contributor.authorMERCE, Manuel
hal.structure.identifierCentre de Recherche Paul Pascal [CRPP]
dc.contributor.authorROUCHER, Armand
hal.structure.identifierCentre de Recherche Paul Pascal [CRPP]
dc.contributor.authorDESTRIBATS, Mathieu
hal.structure.identifierCentre de Recherche Paul Pascal [CRPP]
dc.contributor.authorBACKOV, Renal
hal.structure.identifierCentre de Recherche Paul Pascal [CRPP]
dc.contributor.authorSCHMITT, Veronique
dc.contributor.authorSESCOUSSE, R.
dc.contributor.authorBROUILLET, F.
dc.contributor.authorSARDA, S.
dc.contributor.authorRE, M.I
dc.date.accessioned2022-06-21T14:37:13Z
dc.date.available2022-06-21T14:37:13Z
dc.date.issued2022
dc.identifier.issn9277757en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/140298
dc.description.abstractEnCalcium phosphate (CaP) based bioceramics are widely used as bone substitutes. The most encountered CaP ceramics are obtained from high temperature phases. However, their bioactivity and their association with biomolecules are limited, as well as their bioresorption in-vivo. The aim of this work is to develop biomimetic low temperature apatites ceramics with tunable porosity via biocompatible high internal phase Pickering emulsions. The biocompatible emulsions developed were stabilized by stoichiometric hydroxyapatite (HA) particles. Several parameters (mass of HA particles, oil/water weight ratio, electrolytes concentration in the aqueous phase) were investigated to define the optimized formulation conditions leading to a kinetically stable monodisperse emulsion with a minimum drop diameter of 200 µm and drops enough percolated to induce interconnected porosity. Two types of porous bioceramics were produced by low temperature processes with controlled composition and porosity, evidenced by X-ray microtomography: calcium phosphate monoliths from an apatitic gel, and silica-HA monoliths via a sol-gel process. These low temperature processes should provide bioceramics able to perform bioactivity and bio-resorption in-vivo, and could prefigure a drug or other therapeutic ions-delivery disposals for filling bone defects in maxillofacial or orthopedic surgery.
dc.language.isoENen_US
dc.subject.enPickering Emulsion
dc.subject.enPorous biomaterials
dc.subject.enBioceramics
dc.subject.enHydroxyapatite
dc.subject.enSol-gel process
dc.title.enPickering emulsion as template for porous bioceramics in the perspective of bone regeneration
dc.title.alternativeColloids Surf. A Physicochem. Eng. Asp.en_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.colsurfa.2022.128748en_US
dc.subject.halChimie/Matériauxen_US
bordeaux.journalColloids and Surfaces Aen_US
bordeaux.page128748en_US
bordeaux.volume643en_US
bordeaux.hal.laboratoriesCentre de Recherche Paul Pascal (CRPP) - UMR 5031en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.teamColloïdes, interfaces, assemblages (CIA)
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Colloids%20and%20Surfaces%20A&rft.date=2022&rft.volume=643&rft.spage=128748&rft.epage=128748&rft.eissn=9277757&rft.issn=9277757&rft.au=PASCAUD,%20K.&MERCE,%20Manuel&ROUCHER,%20Armand&DESTRIBATS,%20Mathieu&BACKOV,%20Renal&rft.genre=article


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