Impact of Intraventricular Septal Fiber Orientation on Cardiac Electromechanical Function.
dc.rights.license | open | en_US |
dc.contributor.author | RODRIGUEZ PADILLA, Jairo | |
dc.contributor.author | PETRAS, Argyrios | |
dc.contributor.author | MAGAT, Julie | |
hal.structure.identifier | Institut de Mathématiques de Bordeaux [IMB] | |
dc.contributor.author | BAYER, Jason
IDREF: 228222478 | |
dc.contributor.author | BIHAN-POUDEC, Yann | |
dc.contributor.author | EL-HAMRANI, Dounia | |
hal.structure.identifier | Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB] | |
dc.contributor.author | RAMLUGUN, Girish | |
dc.contributor.author | NEIC, Aurel | |
dc.contributor.author | AUGUSTIN, Christoph | |
dc.contributor.author | VAILLANT, Fanny | |
dc.contributor.author | CONSTANTIN, Marion | |
hal.structure.identifier | Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB] | |
dc.contributor.author | BENOIST, David | |
dc.contributor.author | POURTAU, Line | |
dc.contributor.author | DUBES, Virginie | |
dc.contributor.author | ROGIER, Julien | |
hal.structure.identifier | Biologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases | |
dc.contributor.author | LABROUSSE, Louis | |
hal.structure.identifier | Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB] | |
dc.contributor.author | BERNUS, Olivier | |
dc.contributor.author | QUESSON, Bruno | |
dc.contributor.author | HAISSAGUERRE, Michel | |
dc.contributor.author | GSELL, Matthias | |
dc.contributor.author | PLANK, Gernot | |
hal.structure.identifier | Centre de résonance magnétique des systèmes biologiques [CRMSB] | |
dc.contributor.author | OZENNE, Valéry | |
dc.contributor.author | VIGMOND, Edward | |
dc.date.accessioned | 2022-04-20T12:51:50Z | |
dc.date.available | 2022-04-20T12:51:50Z | |
dc.date.issued | 2022-03 | |
dc.identifier.issn | 1522-1539 | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/139877 | |
dc.description.abstractEn | Cardiac fiber direction is an important factor determining the propagation of electrical activity, as well as the development of mechanical force. In this paper, we imaged the ventricles of several species with special attention to the intraventricular septum to determine the functional consequences of septal fiber organization. First, we identify a dual-layer organization of the fiber orientation in the intraventricular septum of ex-vivo sheep hearts using diffusion tensor imaging at high field MRI. To expand the scope of the results, we investigate the presence of similar fiber organization on five mammalian species (rat, canine, pig, sheep, human) and highlight the continuity of the layer with the moderator band in large mammalian species. We implemented the measured septal fiber fields in 3D electromechanical computer models to assess the impact of the fiber orientation. The downward fibers produced a diamond activation pattern superficially in the RV. Electromechanically, there was very little change in pressure volume loops although the stress distribution was altered. In conclusion, we clarified that the RV septum has a downwardly directed superficial layer in larger mammalian species, which can have modest effects on stress distribution. | |
dc.language.iso | EN | en_US |
dc.subject.en | Intraventricular Septum | |
dc.subject.en | Fiber Orientation | |
dc.subject.en | Electromechanical models | |
dc.subject.en | Diffusion Tensor imaging | |
dc.subject.en | Normal structural discontinuities | |
dc.title.en | Impact of Intraventricular Septal Fiber Orientation on Cardiac Electromechanical Function. | |
dc.title.alternative | Am J Physiol Heart Circ Physiol | en_US |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1152/ajpheart.00050.2022 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Ingénierie biomédicale | en_US |
dc.identifier.pubmed | 35302879 | en_US |
bordeaux.journal | AJP - Heart and Circulatory Physiology | en_US |
bordeaux.hal.laboratories | Centre de Résonance Magnétique des Systèmes Biologiques (CRMSB) - UMR 5536 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.institution | CNRS | en_US |
bordeaux.institution | INSERM | |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
bordeaux.import.source | pubmed | |
hal.identifier | hal-03647387 | |
hal.version | 1 | |
hal.date.transferred | 2022-04-20T12:51:53Z | |
hal.export | true | |
workflow.import.source | pubmed | |
dc.rights.cc | Pas de Licence CC | en_US |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=AJP%20-%20Heart%20and%20Circulatory%20Physiology&rft.date=2022-03&rft.eissn=1522-1539&rft.issn=1522-1539&rft.au=RODRIGUEZ%20PADILLA,%20Jairo&PETRAS,%20Argyrios&MAGAT,%20Julie&BAYER,%20Jason&BIHAN-POUDEC,%20Yann&rft.genre=article |
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