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dc.rights.licenseopenen_US
dc.contributor.authorMAUBEUGE, N.
hal.structure.identifierIBIO - Plateforme de bio-imagerie en sciences médicales
dc.contributor.authorDELOIRE, Mathilde S.A.
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorBROCHET, Bruno
dc.contributor.authorEHRLE, N.
hal.structure.identifierService de neurologie [Bordeaux]
dc.contributor.authorCHARRE-MORIN, Julie
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorRUET, Aurelie
dc.contributor.authorFOR THE BICAFMS STUDY, Investigators
hal.structure.identifierIBIO - Plateforme de bio-imagerie en sciences médicales
dc.contributor.authorSAUBUSSE, Aurore
dc.date.accessioned2022-03-25T10:49:44Z
dc.date.available2022-03-25T10:49:44Z
dc.date.issued2021-02
dc.identifier.issn2211-0348en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/136537
dc.description.abstractEnBackground : The Minimal Assessment of Cognitive Function in Multiple sclerosis (MACFIMS) is an internationally recognised battery of neuropsychological tests for patients with multiple sclerosis (MS). Objectives : To establish regression-based norms for the MACFIMS in French-speaking healthy subjects (HS) and validate its use in persons with multiple sclerosis (PwMS). Methods : 136 PwMS, including 43 with relapsing-remitting MS, 46 with secondary progressive MS and 45 with primary progressive MS, as well as 276 HS were enrolled. Regression-based norms and validity were established for the seven tests of the MACIMS: the Symbol Digit Modalities Test (SDMT), the Paced Auditory Serial Addition Test (PASAT), the French learning test (FLT) a French-adapted memory test (or the California Verbal Learning Test (CVLT) at re-testing), the Judgment of Line Orientation Test (JLO), the ‘épreuve de classement de cartes de Champagne’ (ECCC), a French adaptation of the DKEF-sorting test, the Brief Visuospatial Memory Test (BVMT-R) and the Controlled Oral Word Association Test (COWAT). Results : Regression-based norms of MACFIMS tests were established in the HS population. The MACFIMS battery was able to identify cognitive impairment (CI) (at least two abnormal tests in different domains) in 32.7% of PwMS. The domains with more frequent impairment were (in descending order): learning followed by IPS, delayed memory, verbal fluency and working memory. Conclusion : This study established the regression-based norms for French subjects of the French adaptation of the MACFIMS and its validity in PwMS.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enCognition
dc.subject.enMacfims
dc.subject.enMultiple sclerosis
dc.subject.enNeuropsychology
dc.subject.enValidation
dc.title.enValidation of the French version of the minimal assessment of cognitive function in multiple sclerosis (MACFIMS)
dc.title.alternativeMult Scler Relat Disorden_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.msard.2020.102692en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed33352358en_US
bordeaux.journalMultiple Sclerosis and Related Disordersen_US
bordeaux.volume48en_US
bordeaux.hal.laboratoriesNeurocentre Magendie - UMR-S 1215en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.institutionCHU de Bordeauxen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDBayer HealthCareen_US
hal.exportfalse
dc.rights.ccCC BYen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Multiple%20Sclerosis%20and%20Related%20Disorders&rft.date=2021-02&rft.volume=48&rft.eissn=2211-0348&rft.issn=2211-0348&rft.au=MAUBEUGE,%20N.&DELOIRE,%20Mathilde%20S.A.&BROCHET,%20Bruno&EHRLE,%20N.&CHARRE-MORIN,%20Julie&rft.genre=article


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