Mostrar el registro sencillo del ítem

Shotgun lipidomics and mass spectrometry imaging unveil diversity and dynamics in Gammarus fossarum lipid composition

dc.rights.licenseopenen_US
dc.contributor.authorFU, Tingting
dc.contributor.authorKNITTELFELDER, Oskar
dc.contributor.authorGEFFARD, Olivier
dc.contributor.authorCLEMENT, Yohann
hal.structure.identifierLaboratoire de biogenèse membranaire [LBM]
dc.contributor.authorTESTET, Eric
IDREF: 03328184X
dc.contributor.authorELIE, Nicolas
dc.contributor.authorTOUBOUL, David
dc.contributor.authorABBACI, Khedidja
dc.contributor.authorSHEVCHENKO, Andrei
dc.contributor.authorLEMOINE, Jerome
dc.contributor.authorCHAUMOT, Arnaud
dc.contributor.authorSALVADOR, Arnaud
dc.contributor.authorDEGLI ESPOSTI, Davide
dc.contributor.authorAYCIRIEX, Sophie
dc.date.accessioned2022-03-11T15:17:05Z
dc.date.available2022-03-11T15:17:05Z
dc.date.issued2021
dc.identifier.issn25890042en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/136450
dc.description.abstractEnSentinel species are playing an indispensable role in monitoring environmental pollution in aquatic ecosystems. Many pollutants found in water prove to be endocrine disrupting chemicals that could cause disruptions in lipid homeostasis in aquatic species. A comprehensive profiling of the lipidome of these species is thus an essential step toward understanding the mechanism of toxicity induced by pollutants. Both the composition and spatial distribution of lipids in freshwater crustacean Gammarus fossarum were extensively examined herein. The baseline lipidome of gammarids of different sex and reproductive stages was established by high throughput shotgun lipidomics. Spatial lipid mapping by high resolution mass spectrometry imaging led to the discovery of sulfate-based lipids in hepato-pancreas and their accumulation in mature oocytes. A diverse and dynamic lipid composition in G. fossarum was uncovered, which deepens our understanding of the biochemical changes during development and which could serve as a reference for future ecotoxicological studies.
dc.description.sponsorshipApproches Protéomique et Lipidomique pour la compréhension des mécanismes moléculaires de toxicité en lien avec l'altération du métabolisme lipidique chez l'espèce sentinelle Gammarus fossarum durant le cycle de reproduction - ANR-18-CE34-0008
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subject.enNM ultraviolet photodissociation
dc.subject.enOvarian maturation
dc.subject.enStructural-characterization
dc.subject.enCrude extracts
dc.subject.enAccumulation
dc.subject.enAmphipoda
dc.subject.enCrustacea
dc.subject.enCrab
dc.subject.enMS
dc.subject.enClassification
dc.title.enShotgun lipidomics and mass spectrometry imaging unveil diversity and dynamics in Gammarus fossarum lipid composition
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.isci.2021.102115en_US
dc.subject.halChimie/Chimie analytiqueen_US
dc.subject.halSciences de l'environnementen_US
dc.identifier.pubmed33615205en_US
bordeaux.journaliScienceen_US
bordeaux.volume24en_US
bordeaux.hal.laboratoriesLaboratoire de Biogenèse Membranaire (LBM) - UMR 5200en_US
bordeaux.issue2en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
dc.rights.ccCC BY-NC-NDen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=iScience&rft.date=2021&rft.volume=24&rft.issue=2&rft.eissn=25890042&rft.issn=25890042&rft.au=FU,%20Tingting&KNITTELFELDER,%20Oskar&GEFFARD,%20Olivier&CLEMENT,%20Yohann&TESTET,%20Eric&rft.genre=article


Archivos en el ítem

Thumbnail
Nombre:
LBM_IS_2021_Fu.pdf
Tamaño:
5.990Mb
Formato:
PDF
Ver/Abrir
Thumbnail
Nombre:
license_rdf
Tamaño:
811bytes
Formato:
application/rdf+xml
Ver/Abrir

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem