Occupational Exposure to Ultrafine Particles and Placental Histopathological Lesions: A Retrospective Study about 130 Cases
| dc.rights.license | open | en_US |
| dc.contributor.author | PASQUIOU, Anais | |
| hal.structure.identifier | Bordeaux Research In Translational Oncology [Bordeaux] [BaRITOn] | |
| dc.contributor.author | PELLUARD, Fanny | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | MANANGAMA DUKI, Guyguy | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | BROCHARD, Patrick | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | AUDIGNON, Sabyne | |
| dc.contributor.author | SENTILHES, Loic | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | DELVA, Fleur | |
| dc.date.accessioned | 2022-01-20T11:28:31Z | |
| dc.date.available | 2022-01-20T11:28:31Z | |
| dc.date.issued | 2021-12-02 | |
| dc.identifier.issn | 1660-4601 (Electronic) 1660-4601 (Linking) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/124454 | |
| dc.description.abstractEn | Ultrafine particles (UFPs) are particles smaller than 100 nanometers that are produced unintentionally during human activities or natural phenomena. They have a higher biological reactivity than bigger particles and can reach the placenta after maternal exposure. One study has shown an association between maternal occupational exposure to UFPs and fetal growth restriction. Yet few studies have focused on the effects of UFP exposure on placental histopathological lesions. The aim of this study was to investigate the association between maternal occupational exposure to UFPs and histopathological lesions of their placenta. The analyses were based on data from the ARTEMIS Center. A job-exposure matrix was used to assess occupational exposure to UFPs. The histopathological placental exam was performed by two pathologists who were blinded to the exposure of each subject. The examination was conducted in accordance with the recommendations of the Amsterdam consensus. The study sample included 130 placentas (30 exposed, 100 unexposed). Maternal occupational exposure to UFPs during pregnancy is significantly associated with placental hypoplasia (the phenomenon affected 61% of the exposed patients and 34% of the unexposed ones, p < 0.01). Further research is needed to explain its pathophysiological mechanisms. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.subject.en | Placenta | |
| dc.subject.en | Particulate matter | |
| dc.subject.en | Occupational exposure | |
| dc.subject.en | Nanoparticles | |
| dc.subject.en | Pathology | |
| dc.title.en | Occupational Exposure to Ultrafine Particles and Placental Histopathological Lesions: A Retrospective Study about 130 Cases | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.3390/ijerph182312719 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 34886445 | en_US |
| bordeaux.journal | International Journal of Environmental Research and Public Health | en_US |
| bordeaux.volume | 18 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.issue | 23 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | EPICENE | en_US |
| bordeaux.team | EPICENE_BPH | |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03537286 | |
| hal.version | 1 | |
| hal.date.transferred | 2022-01-20T11:28:34Z | |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=International%20Journal%20of%20Environmental%20Research%20and%20Public%20Health&rft.date=2021-12-02&rft.volume=18&rft.issue=23&rft.eissn=1660-4601%20(Electronic)%201660-4601%20(Linking)&rft.issn=1660-4601%20(Electronic)%201660-4601%20(Linking)&rft.au=PASQUIOU,%20Anais&PELLUARD,%20Fanny&MANANGAMA%20DUKI,%20Guyguy&BROCHARD,%20Patrick&AUDIGNON,%20Sabyne&rft.genre=article |
