ADVANCED OCT ANALYSIS OF BIOPSY PROVEN VITREORETINAL LYMPHOMA: OCT findings in vitreo-retinal lymphoma
| dc.rights.license | open | en_US |
| dc.contributor.author | PICHI, Francesco | |
| dc.contributor.author | DOLZ-MARCO, Rosa | |
| dc.contributor.author | FRANCIS, Jasmine H. | |
| dc.contributor.author | AU, Adrian | |
| dc.contributor.author | DAVIS, Janet L. | |
| dc.contributor.author | FAWZI, Amani | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | GATTOUSI, Sarra | |
| dc.contributor.author | GOLDSTEIN, Debra A. | |
| dc.contributor.author | KEANE, Pearse A. | |
| dc.contributor.author | MISEROCCHI, Elisabetta | |
| dc.contributor.author | MARCHESE, Alessandro | |
| dc.contributor.author | OHNO-MATSUI, Kyoko | |
| dc.contributor.author | SAGOO, Mandeep S. | |
| dc.contributor.author | SMITH, Scott D. | |
| dc.contributor.author | SOBOL, Ethan K. | |
| dc.contributor.author | TASIOPOULOU, Anastasia | |
| dc.contributor.author | YANG, Xialou | |
| dc.contributor.author | SHIELDS, Carol L. | |
| dc.contributor.author | FREUND, K. Bailey | |
| dc.contributor.author | SARRAF, David | |
| dc.date.accessioned | 2022-01-17T08:31:28Z | |
| dc.date.available | 2022-01-17T08:31:28Z | |
| dc.date.issued | 2022-06 | |
| dc.identifier.issn | 0002-9394 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/124399 | |
| dc.description.abstractEn | IMPORTANCE: Although the diagnosis of vitreoretinal lymphoma (VRL) can be challenging, early detection is critical for visual prognosis. OBJECTIVE: To analyze the spectrum of optical coherence tomography (OCT) findings in patients with biopsy-proven VRL and correlate these features with clinical parameters. DESIGN: Retrospective cross-sectional study SETTING: Multicenter chart review from 13 retina, uveitis and ocular oncology clinics worldwide over an 11-year period (2008-2019). PARTICIPANTS: Patients with a diagnosis of biopsy-proven VRL imaged with OCT at presentation EXPOSURE: The ocular information, systemic information and multimodal retinal imaging findings were collected and studied. MAIN OUTCOME MEASURE: Characteristics of VRL on OCT RESULTS: A total of 182 eyes of 115 patients (63 women, mean age 65 years) were included in this study. The disease was bilateral in 81 (70%) patients, and mean baseline visual acuity (VA) was 0.2±0.89 logMAR (Snellen equivalent of 20/32). At baseline, 38 patients (33%) presented with isolated ocular involvement, 54 (45%) with associated central nervous system (CNS) involvement and 11 (10%) with other systemic lymphomatous involvement and an additional 12 (10%) patients presented with both CNS and other systemic involvement. On OCT, tumor infiltration was identified in various retinal layers including lesions in the sub-retinal pigment epithelium (RPE) compartment (91% of eyes), the subretinal compartment (43% of eyes) and the intraretinal compartment (7% of eyes). CONCLUSIONS AND RELEVANCE: OCT analysis of eyes with vitreoretinal lymphoma identified 3 main regions of retinal infiltration. Sub-RPE location, with or without subretinal infiltration, was the most common pattern of involvement whereas isolated intraretinal infiltration was the least common. | |
| dc.language.iso | EN | en_US |
| dc.title.en | ADVANCED OCT ANALYSIS OF BIOPSY PROVEN VITREORETINAL LYMPHOMA: OCT findings in vitreo-retinal lymphoma | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/j.ajo.2021.11.023 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 34843686 | en_US |
| bordeaux.journal | American Journal of Ophthalmology | en_US |
| bordeaux.page | 16-26 | |
| bordeaux.volume | 238 | |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | LEHA_BPH | |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03528091 | |
| hal.version | 1 | |
| hal.date.transferred | 2022-09-02T13:04:59Z | |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=American%20Journal%20of%20Ophthalmology&rft.date=2022-06&rft.volume=238&rft.spage=16-26&rft.epage=16-26&rft.eissn=0002-9394&rft.issn=0002-9394&rft.au=PICHI,%20Francesco&DOLZ-MARCO,%20Rosa&FRANCIS,%20Jasmine%20H.&AU,%20Adrian&DAVIS,%20Janet%20L.&rft.genre=article |
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