Environnement précoce et vulnérabilité neuropsychiatrique
| dc.rights.license | open | en_US |
| hal.structure.identifier | Nutrition et Neurobiologie intégrée [NutriNeuro] | |
| dc.contributor.author | RINCEL, Marion | |
| hal.structure.identifier | Nutrition et Neurobiologie intégrée [NutriNeuro] | |
| dc.contributor.author | LEPINAY, Amandine | |
| dc.contributor.author | GABORY, Anne | |
| dc.contributor.author | THEODOROU, Vassilia | |
| hal.structure.identifier | Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB] | |
| dc.contributor.author | KOEHL, Muriel | |
| dc.contributor.author | DAUGE, Valérie | |
| dc.contributor.author | MACCARI, Stefania | |
| hal.structure.identifier | Nutrition et Neurobiologie intégrée [NutriNeuro] | |
| dc.contributor.author | DARNAUDERY, Muriel
IDREF: 124892264 | |
| dc.date.accessioned | 2022-01-14T08:47:35Z | |
| dc.date.available | 2022-01-14T08:47:35Z | |
| dc.date.issued | 2016-01-01 | |
| dc.identifier.issn | 1958-5381 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/124380 | |
| dc.description.abstract | Du fait de son immaturité à la naissance, le nouveau-né est totalement dépendant des soins parentaux pour sa survie et pour son développement cérébral. Des altérations de la qualité de l’environnement précoce, non seulement lors de l’enfance, mais également en période prénatale, ont un impact, à long terme, sur la santé. Récemment, chez l’animal, des travaux ont mis en évidence des modulations épigénétiques après des stress précoces qui pourraient se transmettre sur plusieurs générations, via des modifications dans les cellules germinales. | |
| dc.description.abstractEn | The human newborn is highly dependent on parental care for its survival but also for the healthy development of its brain. A large body of literature demonstrates the impact of early life adversity, even during the prenatal period, on the adult's health. The susceptibility to neuropsychiatric diseases is often potentiated by early stress. If there is an agreement that a critical developmental period exists, the mechanisms underlying the long term effects of early life adversity are still poorly understood. Recent studies in animals highlight the involvement of epigenetic processes in the transmission of such vulnerabilities, notably via modifications in germ cells, which can be transmitted in the next generations. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | Adult | |
| dc.subject.en | Animals | |
| dc.subject.en | Brain | |
| dc.subject.en | Disease Models | |
| dc.subject.en | Animal | |
| dc.subject.en | Disease Susceptibility | |
| dc.subject.en | Epigenesis | |
| dc.subject.en | Genetic | |
| dc.subject.en | Female | |
| dc.subject.en | Humans | |
| dc.subject.en | Infant | |
| dc.subject.en | Newborn | |
| dc.subject.en | Mental Disorders | |
| dc.subject.en | Pregnancy | |
| dc.subject.en | Prenatal Exposure Delayed Effects | |
| dc.subject.en | Stress | |
| dc.subject.en | Psychological | |
| dc.title | Environnement précoce et vulnérabilité neuropsychiatrique | |
| dc.title.en | [Early life stressful experiences and neuropsychiatric vulnerability: evidences from human and animal models]. | |
| dc.title.alternative | Med Sci (Paris) | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1051/medsci/20163201015 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC] | en_US |
| dc.identifier.pubmed | 26850613 | en_US |
| bordeaux.journal | médecine/sciences | en_US |
| bordeaux.page | 93-9 | en_US |
| bordeaux.volume | 32 | en_US |
| bordeaux.hal.laboratories | NutriNeurO (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286 | en_US |
| bordeaux.issue | 1 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INRAE | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | pubmed | |
| hal.export | false | |
| workflow.import.source | pubmed | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.title=Environnement%20pr%C3%A9coce%20et%20vuln%C3%A9rabilit%C3%A9%20neuropsychiatrique&rft.atitle=Environnement%20pr%C3%A9coce%20et%20vuln%C3%A9rabilit%C3%A9%20neuropsychiatrique&rft.jtitle=m%C3%A9decine/sciences&rft.date=2016-01-01&rft.volume=32&rft.issue=1&rft.spage=93-9&rft.epage=93-9&rft.eissn=1958-5381&rft.issn=1958-5381&rft.au=RINCEL,%20Marion&LEPINAY,%20Amandine&GABORY,%20Anne&THEODOROU,%20Vassilia&KOEHL,%20Muriel&rft.genre=article |
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