Functionalisation of the non-reducing end of chitin by selective periodate oxidation: A new approach to form complex block polysaccharides and water-soluble chitin-based block polymers
| dc.rights.license | open | en_US |
| hal.structure.identifier | Norwegian University of Science and Technology [Trondheim] [NTNU] | |
| dc.contributor.author | MO, Ingrid Vikøren | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
| dc.contributor.author | SCHATZ, Christophe | |
| hal.structure.identifier | Norwegian University of Science and Technology [Trondheim] [NTNU] | |
| dc.contributor.author | CHRISTENSEN, Bjørn E. | |
| dc.date.accessioned | 2022-01-04T18:58:07Z | |
| dc.date.available | 2022-01-04T18:58:07Z | |
| dc.date.issued | 2021-05-13 | |
| dc.identifier.issn | 0144-8617 | en_US |
| dc.identifier.uri | oai:crossref.org:10.1016/j.carbpol.2021.118193 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/124316 | |
| dc.description.abstractEn | Most polysaccharides used in polysaccharide-based block copolymers are attached to the second block through the reducing end, due to the few and highly polysaccharide specific non-reducing end (NRE) functionalisation methods available. Chitin oligomers, prepared by nitrous acid degradation of chitosan (AnM) can, however, be selectively oxidised by periodate since they only possess a single vicinal diol in the NRE residue. Here, we show that both aldehydes formed after oxidation are highly reactive towards bifunctional oxyamines and hydrazide linkers. Sub-stochiometric amounts of linkers resulted in conjugation of AnM oligomers through both chain termini to yield a discrete distribution of ‘polymerised’ oligomers. Such chitin-based block polymers were, in contrast to chitins of the same chain lengths, water-soluble. Oxidised AnM oligomers, functionalised at both termini can also enable the preparation of more complex block polysaccharides such as ABA- or ABC-type. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution-NonCommercial-ShareAlike 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/us/ | * |
| dc.source | crossref | |
| dc.title.en | Functionalisation of the non-reducing end of chitin by selective periodate oxidation: A new approach to form complex block polysaccharides and water-soluble chitin-based block polymers | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/j.carbpol.2021.118193 | en_US |
| dc.subject.hal | Chimie/Polymères | en_US |
| dc.identifier.pubmed | 34119160 | en_US |
| bordeaux.journal | Carbohydrate Polymers | en_US |
| bordeaux.page | 118193 | en_US |
| bordeaux.volume | 267 | en_US |
| bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | Bordeaux INP | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | dissemin | |
| hal.identifier | hal-03511293 | |
| hal.version | 1 | |
| hal.date.transferred | 2022-01-04T18:58:12Z | |
| hal.export | true | |
| workflow.import.source | dissemin | |
| dc.rights.cc | CC BY-NC-SA | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Carbohydrate%20Polymers&rft.date=2021-05-13&rft.volume=267&rft.spage=118193&rft.epage=118193&rft.eissn=0144-8617&rft.issn=0144-8617&rft.au=MO,%20Ingrid%20Vik%C3%B8ren&SCHATZ,%20Christophe&CHRISTENSEN,%20Bj%C3%B8rn%20E.&rft.genre=article |
