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dc.rights.licenseopenen_US
dc.contributor.authorGENOVESI, Simonetta
dc.contributor.authorBORIANI, Giuseppe
dc.contributor.authorCOVIC, Adrian
dc.contributor.authorVERNOOIJ, Robin W M
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorCOMBE, Christian
ORCID: 0000-0002-0360-573X
IDREF: 58708871
dc.contributor.authorBURLACU, Alexandru
dc.contributor.authorDAVENPORT, Andrew
dc.contributor.authorKANBAY, Mehmet
dc.contributor.authorKIRMIZIS, Dimitrios
dc.contributor.authorSCHNEDITZ, Daniel
dc.contributor.authorVAN DER SANDE, Frank
dc.contributor.authorBASILE, Carlo
dc.date.accessioned2021-12-21T09:15:00Z
dc.date.available2021-12-21T09:15:00Z
dc.date.issued2021-02-20
dc.identifier.issn1460-2385en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/124247
dc.description.abstractEnSudden cardiac death (SCD) represents a major cause of death in end-stage kidney disease (ESKD). The precise estimate of its incidence is difficult to establish because studies on the incidence of SCD in ESKD are often combined with those related to sudden cardiac arrest (SCA) occurring during a haemodialysis (HD) session. The aim of the European Dialysis Working Group of ERA-EDTA was to critically review the current literature examining the causes of extradialysis SCD and intradialysis SCA in ESKD patients and potential management strategies to reduce the incidence of such events. Extradialysis SCD and intradialysis SCA represent different clinical situations and should be kept distinct. Regarding the problem, numerically less relevant, of patients affected by intradialysis SCA, some modifiable risk factors have been identified, such as a low concentration of potassium and calcium in the dialysate, and some advantages linked to the presence of automated external defibrillators in dialysis units have been documented. The problem of extra-dialysis SCD is more complex. A reduced left ventricular ejection fraction associated with SCD is present only in a minority of cases occurring in HD patients. This is the proof that SCD occurring in ESKD has different characteristics compared with SCD occurring in patients with ischaemic heart disease and/or heart failure and not affected by ESKD. Recent evidence suggests that the fatal arrhythmia in this population may be due more frequently to bradyarrhythmias than to tachyarrhythmias. This fact may partly explain why several studies could not demonstrate an advantage of implantable cardioverter defibrillators in preventing SCD in ESKD patients. Electrolyte imbalances, frequently present in HD patients, could explain part of the arrhythmic phenomena, as suggested by the relationship between SCD and timing of the HD session. However, the high incidence of SCD in patients on peritoneal dialysis suggests that other risk factors due to cardiac comorbidities and uraemia per se may contribute to sudden mortality in ESKD patients.
dc.language.isoENen_US
dc.subject.enArrhythmias
dc.subject.enCardiac
dc.subject.enDeath
dc.subject.enSudden
dc.subject.enCardiac
dc.subject.enDisease Management
dc.subject.enHumans
dc.subject.enKidney Failure
dc.subject.enChronic
dc.subject.enRenal Dialysis
dc.subject.enRisk Factors
dc.title.enSudden cardiac death in dialysis patients: different causes and management strategies.
dc.title.alternativeNephrol Dial Transplanten_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1093/ndt/gfz182en_US
dc.subject.halSciences du Vivant [q-bio]/Biotechnologiesen_US
dc.identifier.pubmed31538192en_US
bordeaux.journalNephrology Dialysis Transplantationen_US
bordeaux.page396-405en_US
bordeaux.volume36en_US
bordeaux.hal.laboratoriesBioingénierie Tissulaire (BioTis) - UMR_S 1026en_US
bordeaux.issue3en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.institutionINSERMen_US
bordeaux.institutionCHU de Bordeauxen_US
bordeaux.institutionInstitut Bergoniéen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.identifierhal-03498684
hal.version1
hal.date.transferred2021-12-21T09:15:05Z
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nephrology%20Dialysis%20Transplantation&rft.date=2021-02-20&rft.volume=36&rft.issue=3&rft.spage=396-405&rft.epage=396-405&rft.eissn=1460-2385&rft.issn=1460-2385&rft.au=GENOVESI,%20Simonetta&BORIANI,%20Giuseppe&COVIC,%20Adrian&VERNOOIJ,%20Robin%20W%20M&COMBE,%20Christian&rft.genre=article


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