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dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorJAQUET, Antoine
ORCID: 0000-0002-1127-220X
IDREF: 120590344
dc.contributor.authorMUULA, Guy
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorEKOUEVI, Didier Koumavi
dc.contributor.authorWANDELER, Gilles
dc.date.accessioned2021-11-08T10:13:50Z
dc.date.available2021-11-08T10:13:50Z
dc.date.issued2021-09
dc.identifier.issn2196-2995 (Print)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/123770
dc.description.abstractEnPURPOSE OF REVIEW: The purpose of our review was to summarize current recommendations on testing strategies, antiviral therapy eligibility and monitoring, and prevention of mother-to-child transmission of chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, and to highlight major research gaps in low and middle-income countries (LMIC), with a particular focus on sub-Saharan Africa (SSA). RECENT FINDINGS: While data on the prevalence of HBV and HCV infections in LMIC are increasing, current knowledge on liver-related complications as well as on treatment outcomes remains limited. Furthermore, very little information is available on the feasibility and cost-effectiveness of large-scale testing and management strategies in high-prevalence settings. The availability of policy-relevant data is particularly scarce in SSA, which accounts for a significant part of the global burden of chronic viral hepatitis. SUMMARY: Current recommendations on the management and monitoring of chronic viral hepatitis rely mainly on data from high-income settings. The global elimination of viral hepatitis will only be achieved if prevention, testing, and treatment strategies tailored to specific LMIC are implemented. In order to inform scalable and cost-effective interventions, dedicated research initiatives have to be undertaken. Future studies will have to include the evaluation of innovative testing strategies, the validation of simplified methods to diagnose liver cirrhosis and hepatocellular carcinoma, and the monitoring of long-term treatment outcomes and toxicity. In addition, national plans to achieve the elimination of HBV mother-to-child transmission are urgently needed, including effective ways to test pregnant women, treat those who are eligible, and ensure birth dose vaccination is given to all newborns.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subjectElimination
dc.subjectViral hepatitis
dc.subjectResearch gaps
dc.subjectLMIC
dc.subjectSub-Saharan Africa
dc.title.enElimination of Viral Hepatitis in Low and Middle-Income Countries: Epidemiological Research Gaps
dc.typeArticle de revueen_US
dc.identifier.doi10.1007/s40471-021-00273-6en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed34532216en_US
bordeaux.journalCurrent epidemiology reportsen_US
bordeaux.page89-96en_US
bordeaux.volume8en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue3en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamIDLICen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03418982
hal.version1
hal.date.transferred2021-11-08T10:13:55Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Current%20epidemiology%20reports&rft.date=2021-09&rft.volume=8&rft.issue=3&rft.spage=89-96&rft.epage=89-96&rft.eissn=2196-2995%20(Print)&rft.issn=2196-2995%20(Print)&rft.au=JAQUET,%20Antoine&MUULA,%20Guy&EKOUEVI,%20Didier%20Koumavi&WANDELER,%20Gilles&rft.genre=article


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