Interstitial Lung Abnormalities Detected by CT in Asbestos-Exposed Subjects Are More Likely Associated to Age
| dc.rights.license | open | en_US |
| hal.structure.identifier | Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB] | |
| dc.contributor.author | LAURENT, Francois | |
| hal.structure.identifier | Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB] | |
| dc.contributor.author | BENLALA, Ilyes | |
| hal.structure.identifier | Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB] | |
| dc.contributor.author | DOURNES, Gael | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | GRAMOND, Celine | |
| dc.contributor.author | THAON, Isabelle | |
| dc.contributor.author | CLIN, Benedicte | |
| dc.contributor.author | BROCHARD, Patrick
ORCID: 0000-0002-5056-1397 IDREF: 134088123 | |
| dc.contributor.author | GISLARD, Antoine | |
| dc.contributor.author | ANDUJAR, Pascal | |
| dc.contributor.author | CHAMMINGS, Soizick | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | GALLET, Justine | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | LACOURT, Aude | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | DELVA, Fleur | |
| dc.contributor.author | PARIS, Christophe | |
| dc.contributor.author | FERRETTI, Gilbert | |
| dc.contributor.author | PAIRON, Jean-Claude | |
| dc.date.accessioned | 2021-10-11T08:05:16Z | |
| dc.date.available | 2021-10-11T08:05:16Z | |
| dc.date.issued | 2021-07-15 | |
| dc.identifier.issn | 2077-0383 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/112712 | |
| dc.description.abstractEn | OBJECTIVE: the aim of this study was to evaluate the association between interstitial lung abnormalities, asbestos exposure and age in a population of retired workers previously occupationally exposed to asbestos. METHODS: previously occupationally exposed former workers to asbestos eligible for a survey conducted between 2003 and 2005 in four regions of France, underwent chest CT examinations and pulmonary function testing. Industrial hygienists evaluated asbestos exposure and calculated for each subject a cumulative exposure index (CEI) to asbestos. Smoking status information was also collected in this second round of screening. Expert radiologists performed blinded independent double reading of chest CT-scans and classified interstitial lung abnormalities into: no abnormality, minor interstitial findings, interstitial findings inconsistent with UIP, possible or definite UIP. In addition, emphysema was assessed visually (none, minor: emphysema <25%, moderate: between 25 and 50% and severe: >50% of the lung). Logistic regression models adjusted for age and smoking were used to assess the relationship between interstitial lung abnormalities and occupational asbestos exposure. RESULTS: the study population consisted of 2157 male subjects. Interstitial lung abnormalities were present in 365 (16.7%) and emphysema in 444 (20.4%). Significant positive association was found between definite or possible UIP pattern and age (OR adjusted =1.08 (95% CI: 1.02-1.13)). No association was found between interstitial abnormalities and CEI or the level of asbestos exposure. CONCLUSION: presence of interstitial abnormalities at HRCT was associated to aging but not to cumulative exposure index in this cohort of former workers previously occupationally exposed to asbestos. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.subject.en | Asbestos-exposition | |
| dc.subject.en | HRCT | |
| dc.subject.en | Asbestosis | |
| dc.title.en | Interstitial Lung Abnormalities Detected by CT in Asbestos-Exposed Subjects Are More Likely Associated to Age | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.3390/jcm10143130 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 34300298 | en_US |
| bordeaux.journal | Journal of Clinical Medicine | en_US |
| bordeaux.volume | 10 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.issue | 14 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | EPICENE_BPH | |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.export | false | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20Clinical%20Medicine&rft.date=2021-07-15&rft.volume=10&rft.issue=14&rft.eissn=2077-0383&rft.issn=2077-0383&rft.au=LAURENT,%20Francois&BENLALA,%20Ilyes&DOURNES,%20Gael&GRAMOND,%20Celine&THAON,%20Isabelle&rft.genre=article |
