Food for mood: relevance of nutritional omega-3 fatty acids for depression and anxiety
| dc.rights.license | open | en_US |
| hal.structure.identifier | Nutrition et Neurobiologie intégrée [NutriNeuro] | |
| dc.contributor.author | LARRIEU, Thomas | |
| hal.structure.identifier | Nutrition et Neurobiologie intégrée [NutriNeuro] | |
| dc.contributor.author | LAYE, Sophie
ORCID: 0000-0002-3843-1012 IDREF: 11366883X | |
| dc.date.accessioned | 2021-09-22T15:29:06Z | |
| dc.date.available | 2021-09-22T15:29:06Z | |
| dc.date.issued | 2018 | |
| dc.identifier.issn | 1664-042X | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/112343 | |
| dc.description.abstractEn | The central nervous system (CNS) has the highest concentration of lipids in the organism after adipose tissue. Among these lipids, the brain is particularly enriched with polyunsaturated fatty acids (PUFAs) represented by the omega-6 (omega 6) and omega-3 (omega 3) series. These PUFAs include arachidonic acid (AA) and docosahexaenoic acid (DHA), respectively. PUFAs have received substantial attention as being relevant to many brain diseases, including anxiety and depression. This review addresses an important question in the area of nutritional neuroscience regarding the importance of omega 3 PUFAs in the prevention and/or treatment of neuropsychiatric diseases, mainly depression and anxiety. In particular, it focuses on clinical and experimental data linking dietary intake of omega 3 PUFAs and depression or anxiety. In particular, we will discuss recent experimental data highlighting how omega 3 PUFAs can modulate neurobiological processes involved in the pathophysiology of anxiety and depression. Potential mechanisms involved in the neuroprotective and corrective activity of omega 3 PUFAs in the brain are discussed, in particular the sensing activity of free fatty acid receptors and the activity of the PUFAs-derived endocannabinoid system and the hypothalamic-pituitary-adrenal axis. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.subject.en | depression | |
| dc.subject.en | anxiety | |
| dc.subject.en | HPA axis | |
| dc.subject.en | DHA | |
| dc.subject.en | endocannabinoids | |
| dc.subject.en | mood disorders | |
| dc.subject.en | nutrient sensing | |
| dc.subject.en | omega-3 fatty acid | |
| dc.title.en | Food for mood: relevance of nutritional omega-3 fatty acids for depression and anxiety | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.3389/fphys.2018.01047 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC] | en_US |
| dc.identifier.pubmed | 30127751 | en_US |
| bordeaux.journal | Frontiers in Physiology | en_US |
| bordeaux.page | 1-15 | en_US |
| bordeaux.volume | 9 | en_US |
| bordeaux.hal.laboratories | NutriNeurO (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INRAE | en_US |
| bordeaux.team | Psychoneuroimmunologie et Nutrition: Approches expérimentales et cliniques | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.identifier.funderID | Agence Nationale de la Recherche | en_US |
| bordeaux.identifier.funderID | Institut National de la Recherche Agronomique | en_US |
| bordeaux.identifier.funderID | Fondation pour la Recherche Médicale | en_US |
| bordeaux.identifier.funderID | Conseil Régional Aquitaine | en_US |
| bordeaux.identifier.funderID | Société Française de Nutrition | en_US |
| bordeaux.identifier.funderID | LabEx BRAIN | en_US |
| hal.export | false | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Frontiers%20in%20Physiology&rft.date=2018&rft.volume=9&rft.spage=1-15&rft.epage=1-15&rft.eissn=1664-042X&rft.issn=1664-042X&rft.au=LARRIEU,%20Thomas&LAYE,%20Sophie&rft.genre=article |
