Mostrar el registro sencillo del ítem

Bioactive lipids as new class of microglial modulators: When nutrition meets neuroimunology

dc.rights.licenseopenen_US
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorNADJAR, Agnes
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorLEYROLLE, Quentin
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorJOFFRE, Corinne
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorLAYE, Sophie
ORCID: 0000-0002-3843-1012
IDREF: 11366883X
dc.date.accessioned2021-09-03T14:50:51Z
dc.date.available2021-09-03T14:50:51Z
dc.date.issued2017
dc.identifier.issn1878-4216en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/112085
dc.description.abstractEnWithin the central nervous system the traditional role of microglia has been in brain infection and disease, phagocytosing debris and secreting factors to modify disease progression. More recently, microglia have been found to be important for normal brain development, circuit refinement, and synaptic plasticity in ways that were previously unsuspected. Hence, the brain innate immune system appears to be key in all situations, ranging from physiology to pathology. This unique feature of microglia is established by the wide array of receptors it is equipped with to sense molecular patterns. This includes receptors to most if not all neurotransmitters, neuromodulators and purines. We here review novel, yet extensive literature on a new class of microglia modulators, namely bioactive fatty acids. These lipids are issued from metabolism of nutrients and can cross the blood brain barrier to reach the CNS. They appear to be direct modulators of microglial activity, triggering/inhibiting inflammatory processes or enhancing/inhibiting the ability of these cells to respond to hazardous agents.
dc.language.isoENen_US
dc.subject.enAnimals
dc.subject.enBrain
dc.subject.enFatty acid
dc.subject.enFatty Acids
dc.subject.enHumans
dc.subject.enInflammation
dc.subject.enLipids
dc.subject.enMicroglia
dc.subject.enNeuroimmunomodulation
dc.subject.enNutrition
dc.title.enBioactive lipids as new class of microglial modulators: When nutrition meets neuroimunology
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.pnpbp.2016.07.004en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed27392882en_US
bordeaux.journalProgress in Neuro-Psychopharmacology & Biological Psychiatryen_US
bordeaux.page19-26en_US
bordeaux.volume79en_US
bordeaux.hal.laboratoriesNutriNeurO (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286en_US
bordeaux.issuePt Aen_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINRAEen_US
bordeaux.teamPsychoneuroimmunologie et Nutrition: Approches expérimentales et cliniquesen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDInstitut National de la Recherche Agronomiqueen_US
bordeaux.identifier.funderIDUniversité de Bordeauxen_US
bordeaux.identifier.funderIDAgence Nationale de la Rechercheen_US
bordeaux.identifier.funderIDConseil Régional, Île-de-Franceen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Progress%20in%20Neuro-Psychopharmacology%20&%20Biological%20Psychiatry&rft.date=2017&rft.volume=79&rft.issue=Pt%20A&rft.spage=19-26&rft.epage=19-26&rft.eissn=1878-4216&rft.issn=1878-4216&rft.au=NADJAR,%20Agnes&LEYROLLE,%20Quentin&JOFFRE,%20Corinne&LAYE,%20Sophie&rft.genre=article


Archivos en el ítem

ArchivosTamañoFormatoVer

No hay archivos asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem