Afficher la notice abrégée

Risk Factors of Early Mortality and Morbidity in Esophageal Atresia with Distal Tracheoesophageal Fistula: A Population-Based Cohort Study

dc.rights.licenseopenen_US
dc.contributor.authorSFEIR, Rony
dc.contributor.authorROUSSEAU, Veronique
dc.contributor.authorBONNARD, Arnaud
dc.contributor.authorGELAS, Thomas
dc.contributor.authorAUMAR, Madeleine
dc.contributor.authorPANAIT, Nicoleta
dc.contributor.authorPIOLAT, Christian
dc.contributor.authorIRTAN, Sabine
dc.contributor.authorFOUQUET, Virginie
dc.contributor.authorLEMANDAT, Aurelie
dc.contributor.authorDE NAPOLI, Stephan
dc.contributor.authorHABONIMANA, Edouard
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLAMIREAU, Thierry
dc.contributor.authorLEMELLE, Jean-Louis
dc.contributor.authorEL BAZ, Frederic
dc.contributor.authorTALON, Isabelle
dc.contributor.authorPOLIMEROL, Marie-Laurence
dc.contributor.authorALLAL, Hussein
dc.contributor.authorBUISSON, Philippe
dc.contributor.authorPETIT, Thierry
dc.contributor.authorLOUIS, David
dc.contributor.authorLARDY, Hubert
dc.contributor.authorSCHMITT, Francoise
dc.contributor.authorLEVARD, Guillaume
dc.contributor.authorSCALABRE, Aurelien
dc.contributor.authorMICHEL, Jean-Luc
dc.contributor.authorJABY, Olivier
dc.contributor.authorPELATAN, Cecile
dc.contributor.authorDE VRIES, Philine
dc.contributor.authorBORDERON, Corinne
dc.contributor.authorFOURCADE, Laurent
dc.contributor.authorBREAUD, Jean
dc.contributor.authorPOUZAC, Myriam
dc.contributor.authorTOLG, Cecilia
dc.contributor.authorCHAUSSY, Yann
dc.contributor.authorJOCHAULT RITZ, Sandy
dc.contributor.authorLAPLACE, Christophe
dc.contributor.authorDRUMEZ, Elodie
dc.contributor.authorGOTTRAND, Frederic
dc.date.accessioned2021-08-30T09:40:15Z
dc.date.available2021-08-30T09:40:15Z
dc.date.issued2021-07
dc.identifier.issn1097-6833 (Electronic) 0022-3476 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/110248
dc.description.abstractEnOBJECTIVE: To identify the risk factors for early mortality and morbidity in a population with distal esophageal atresia (EA)-tracheoesophageal fistula. STUDY DESIGN: Cohort study from a national register. Main outcomes and measures included early mortality, hospital length of stay (LoS), need for nutritional support at 1 year of age as a proxy measure of morbidity, and complications during the first year of life. RESULTS: In total, 1008 patients with a lower esophageal fistula were included from January 1, 2008, to December 31, 2014. The survival rate at 3 months was 94.9%. The cumulative hospital LoS was 31.0 (17.0-64.0) days. Multivariate analysis showed that intrahospital mortality at 3 months was associated with low birth weight (OR 0.52, 95% CI [0.38-0.72], P < .001), associated cardiac abnormalities (OR 6.09 [1.96-18.89], P = .002), and prenatal diagnosis (OR 2.96 [1.08-8.08], P = .034). LoS was associated with low birth weight (-0.225 ± 0.035, P < .001), associated malformations (0.082 ± 0.118, P < .001), surgical difficulties (0.270 ± 0.107, P < .001), and complications (0.535 ± 0.099, P < .001) during the first year of life. Predictive factors for dependency on nutrition support at 1 year of age were complications before 1 year (OR 3.28 [1.23-8.76], P < .02) and initial hospital LoS (OR 1.96 [1.15-3.33], P < .01). CONCLUSIONS: EA has a low rate of early mortality, but morbidity is high during the first year of life. Identifying factors associated with morbidity may help to improve neonatal care of this population.
dc.language.isoENen_US
dc.subject.enCongenital abnormalities
dc.subject.enPopulation-based registry
dc.subject.enPrenatal diagnosis
dc.title.enRisk Factors of Early Mortality and Morbidity in Esophageal Atresia with Distal Tracheoesophageal Fistula: A Population-Based Cohort Study
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.jpeds.2021.02.064en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed33667507en_US
bordeaux.journalThe Journal of Pediatricsen_US
bordeaux.page99-105.e1en_US
bordeaux.volume234en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamLEHA_BPH
bordeaux.teamLEHA_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03328659
hal.version1
hal.date.transferred2021-08-30T09:40:20Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&amp;rft_val_fmt=info:ofi/fmt:kev:mtx:journal&amp;rft.jtitle=The%20Journal%20of%20Pediatrics&amp;rft.date=2021-07&amp;rft.volume=234&amp;rft.spage=99-105.e1&amp;rft.epage=99-105.e1&amp;rft.eissn=1097-6833%20(Electronic)%200022-3476%20(Linking)&amp;rft.issn=1097-6833%20(Electronic)%200022-3476%20(Linking)&amp;rft.au=SFEIR,%20Rony&amp;ROUSSEAU,%20Veronique&amp;BONNARD,%20Arnaud&amp;GELAS,%20Thomas&amp;AUMAR,%20Madeleine&amp;rft.genre=article


Fichier(s) constituant ce document

FichiersTailleFormatVue

Il n'y a pas de fichiers associés à ce document.

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée