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Quantitative Side-Chain Modifications of Methionine-Containing Elastin-Like Polypeptides as a Versatile Tool to Tune Their Properties

dc.contributor.authorKRAMER, Jessica R.
dc.contributor.authorPETITDEMANGE, Rosine
dc.contributor.authorBATAILLE, Laure
hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorBATHANY, Katell
dc.contributor.authorWIROTIUS, Anne-Laure
dc.contributor.authorGARBAY, Bertrand
ORCID: 0000-0001-5756-2627
IDREF: 033777551
dc.contributor.authorDEMING, Timothy J.
dc.contributor.authorGARANGER, Elisabeth
IDREF: 089451740
dc.contributor.authorLECOMMANDOUX, Sebastien
dc.date.accessioned2020-09-03T08:02:07Z
dc.date.available2020-09-03T08:02:07Z
dc.date.issued2015
dc.identifier.issn2161-1653
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/10968
dc.description.abstractEnTuning the lower critical solution temperature (LCST) of temperature-responsive recombinant elastin-like polypeptides has usually been achieved by designing different protein sequences, in terms of amino acid composition and length, implying tedious molecular cloning steps. In the present work, we have explored the chemoselective alkylation of methionine as an easy means to modify elastin repeat side chains and easily modulate the LCST of the polypeptides. Such a versatile synthetic method shall practically be exploited to modulate any properties of recombinant polymers.
dc.language.isoen
dc.title.enQuantitative Side-Chain Modifications of Methionine-Containing Elastin-Like Polypeptides as a Versatile Tool to Tune Their Properties
dc.typeArticle de revue
dc.identifier.doi10.1021/acsmacrolett.5b00651
dc.subject.halChimie/Matériaux
bordeaux.journalACS Macro Letters
bordeaux.page1283-1286
bordeaux.volume4
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248*
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN, UMR 5248)
bordeaux.issue11
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=ACS%20Macro%20Letters&rft.date=2015&rft.volume=4&rft.issue=11&rft.spage=1283-1286&rft.epage=1283-1286&rft.eissn=2161-1653&rft.issn=2161-1653&rft.au=KRAMER,%20Jessica%20R.&PETITDEMANGE,%20Rosine&BATAILLE,%20Laure&BATHANY,%20Katell&WIROTIUS,%20Anne-Laure&rft.genre=article


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