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Effects of Age, Level of Education and HIV Status on Cognitive Performance in West African Older Adults: The West Africa IeDEA Cohort Collaboration

dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorBERNARD, Charlotte
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorFONT, Helene
dc.contributor.authorDIALLO, Z.
dc.contributor.authorAHONON, R.
dc.contributor.authorTINE, J. M.
dc.contributor.authorABOUO, F. N.
dc.contributor.authorTANON, A.
dc.contributor.authorMESSOU, E.
dc.contributor.authorSEYDI, M.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDABIS, Francois
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDARTIGUES, Jean-Francois
ORCID: 0000-0001-9482-5529
IDREF: 058586105
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDE REKENEIRE, Nathalie
dc.contributor.authorIE, D. E. A. West Africa Cohort Collaboration
dc.date.accessioned2021-07-15T09:21:42Z
dc.date.available2021-07-15T09:21:42Z
dc.date.issued2021-05-29
dc.identifier.issn1090-7165en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/109247
dc.description.abstractEnAn in-depth understanding of the impact of aging, cognitive reserve, and HIV status on cognitive function is needed in older West African adults. Ninety-nine HIV-negative and 334 HIV-positive adults aged ≥ 50 years were enrolled in three clinics (Senegal and Côte d'Ivoire) participating in the IeDEA West Africa collaboration. All subjects underwent the Free and Cued Selective Reminding Test (FCSRT) and the Isaacs Set Test (IST). Age (both linear and quadratic), education level, and HIV status effects on Z-scores were assessed using multivariate linear regression models. Interactions between HIV status and age or educational level were tested. In the present cohort of older West African adults, the role of age and educational level on episodic memory and verbal fluency was observed without revealing an interaction between HIV status and age effect. As age had quadratic effects, older HIV-positive adults should not be considered as a unique group irrespective of their age. Low-educated HIV-positive patients had the lowest verbal fluency performance compared to others. Further studies are needed to duplicate these results. In clinical settings, screening and adapted programs focusing on improving cognition in those patients are needed.
dc.language.isoENen_US
dc.subject.enCognition
dc.subject.enAging
dc.subject.enEducation level
dc.subject.enHIV status
dc.subject.enWest Africa
dc.title.enEffects of Age, Level of Education and HIV Status on Cognitive Performance in West African Older Adults: The West Africa IeDEA Cohort Collaboration
dc.typeArticle de revueen_US
dc.identifier.doi10.1007/s10461-021-03309-6en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed34050826en_US
bordeaux.journalAIDS and Behavioren_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamIDLICen_US
bordeaux.teamIeDEAen_US
bordeaux.teamSEPIAen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03286878
hal.version1
hal.date.transferred2021-07-15T09:21:46Z
hal.exporttrue
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