Mostrar el registro sencillo del ítem

Synthesis and Conformational Analysis of Quinoline-Oxazole Peptides

dc.contributor.authorKUDO, Mayumi
dc.contributor.authorLOPEZ, Daniel Carbajo
dc.contributor.authorMAURIZOT, Victor
dc.contributor.authorMASU, Hyuma
dc.contributor.authorTANATANI, Aya
dc.contributor.authorHUC, Ivan
dc.date.accessioned2020-09-03T07:56:14Z
dc.date.available2020-09-03T07:56:14Z
dc.date.issued2016
dc.identifier.issn1434-193X
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/10853
dc.description.abstractEnThe incorporation of flexible aliphatic units into otherwise rigid aromatic foldamer sequences may result in different outcomes. The flexible units may have conformational preferences of their own that can be expressed orthogonally to those of the aromatic units. Alternatively, the latter may dictate their folding behavior onto the former. Hybrid aliphatic-aromatic peptidic oligomers combining oxazole-based (O) and quinoline-based (Q) amino acids have been synthesized, and their folding behavior has been investigated in solution by NMR spectroscopy and CD spectroscopy, and in the solid state by Xray crystallography. Sequences based on the OQQ repeat motif were shown to fold into a canonical aromatic helix motif dominated by the preferences of the quinoline, whereas sequences based on OQ repetitions preferred to fold into a herringbone helix in which the conformational preference of the oxazole units is also expressed.
dc.language.isoen
dc.title.enSynthesis and Conformational Analysis of Quinoline-Oxazole Peptides
dc.typeArticle de revue
dc.identifier.doi10.1002/ejoc.201600229
dc.subject.halChimie/Matériaux
bordeaux.journalEUROPEAN JOURNAL OF ORGANIC CHEMISTRY
bordeaux.page2457-2466
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248*
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN, UMR 5248)
bordeaux.issue14
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=EUROPEAN%20JOURNAL%20OF%20ORGANIC%20CHEMISTRY&rft.date=2016&rft.issue=14&rft.spage=2457-2466&rft.epage=2457-2466&rft.eissn=1434-193X&rft.issn=1434-193X&rft.au=KUDO,%20Mayumi&LOPEZ,%20Daniel%20Carbajo&MAURIZOT,%20Victor&MASU,%20Hyuma&TANATANI,%20Aya&rft.genre=article


Archivos en el ítem

ArchivosTamañoFormatoVer

No hay archivos asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem