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Clinical presentation, outcomes and factors associated with mortality: A prospective study from three COVID-19 referral care centres in West Africa

dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorJASPARD, Marie
dc.contributor.authorSOW, Mamadou Saliou
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorJUCHET, Sylvain
dc.contributor.authorDIENDERE, Eric
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorSERRA, Beatrice
dc.contributor.authorKOJAN, Richard
dc.contributor.authorSIVAHERA, Billy
dc.contributor.authorMARTIN, Caroline
dc.contributor.authorKINDA, Moumouni
dc.contributor.authorLANG, Hans-Joerg
dc.contributor.authorBANGALY SAKO, Fode
dc.contributor.authorAMARA TRAORE, Fode
dc.contributor.authorKOUMBEM, Eudoxie
dc.contributor.authorTINTO, Halidou
dc.contributor.authorSANOU, Adama
dc.contributor.authorSONDO, Apoline
dc.contributor.authorKABORE, Flavien
dc.contributor.authorDONAMOU, Joseph
dc.contributor.authorGUILAVOGUI, Jean-Paul-Yassa
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorVELARDO, Fanny
dc.contributor.authorBICABA, Brice
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorMARCY, Olivier
dc.contributor.authorAUGIER, Augustin
dc.contributor.authorSAYADI, Sani
dc.contributor.authorPODA, Armel
dc.contributor.authorKEITA, Sakoba
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorANGLARET, Xavier
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorMALVY, Denis
dc.date.accessioned2021-07-09T09:04:27Z
dc.date.available2021-07-09T09:04:27Z
dc.date.issued2021-07
dc.identifier.issn1201-9712en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/106487
dc.description.abstractEnOBJECTIVES: The overall death toll from COVID-19 in Africa is reported to be low but there is little individual-level evidence on the severity of the disease. This study examined the clinical spectrum and outcome of patients monitored in COVID-19 care centres (CCCs) in two West-African countries. METHODS: Burkina Faso and Guinea set up referral CCCs to hospitalise all symptomatic SARS-CoV-2 carriers, regardless of the severity of their symptoms. Data collected from hospitalised patients by November 2020 are presented. RESULT: A total of 1,805 patients (64% men, median age 41 years) were admitted with COVID-19. Symptoms lasted for a median of 7 days (IQR 4-11). During hospitalisation, 443 (25%) had a SpO2 < 94% at least once, 237 (13%) received oxygen and 266 (15%) took corticosteroids. Mortality was 5% overall, and 1%, 5% and 14% in patients aged <40, 40-59 and ≥60 years, respectively. In multivariable analysis, the risk of death was higher in men (aOR 2.0, 95% CI 1.1; 3.6), people aged ≥60 years (aOR 2.9, 95% CI 1.7; 4.8) and those with chronic hypertension (aOR 2.1, 95% CI 1.2; 3.4). CONCLUSION: COVID-19 is as severe in Africa as elsewhere, and there must be more vigilance for common risk factors such as older age and hypertension.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enSARS-Cov-2
dc.subject.enCOVID-19
dc.subject.enSub-Saharan Africa
dc.subject.enMortality
dc.subject.enComorbidities
dc.title.enClinical presentation, outcomes and factors associated with mortality: A prospective study from three COVID-19 referral care centres in West Africa
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.ijid.2021.05.024en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed34000419en_US
bordeaux.journalInternational Journal of Infectious Diseasesen_US
bordeaux.page45-52en_US
bordeaux.volume108en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamIDLICen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03282438
hal.version1
hal.date.transferred2021-07-09T09:04:32Z
hal.exporttrue
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