JASPARD, Marie; SOW, Mamadou Saliou; JUCHET, Sylvain; DIENDERE, Eric; SERRA, Beatrice; KOJAN, Richard; SIVAHERA, Billy; MARTIN, Caroline; KINDA, Moumouni; LANG, Hans-Joerg; BANGALY SAKO, Fode; AMARA TRAORE, Fode; KOUMBEM, Eudoxie; TINTO, Halidou; SANOU, Adama; SONDO, Apoline; KABORE, Flavien; DONAMOU, Joseph; GUILAVOGUI, Jean-Paul-Yassa; VELARDO, Fanny; BICABA, Brice; MARCY, Olivier; AUGIER, Augustin; SAYADI, Sani; PODA, Armel; KEITA, Sakoba; ANGLARET, Xavier; MALVY, Denis

doi:10.1016/j.ijid.2021.05.024

Bordeaux population health [BPH]

SOW, Mamadou Saliou

JUCHET, Sylvain
Bordeaux population health [BPH]

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Article de revue

Ce document a été publié dans

International Journal of Infectious Diseases. 2021-07, vol. 108, p. 45-52

Résumé en anglais

OBJECTIVES: The overall death toll from COVID-19 in Africa is reported to be low but there is little individual-level evidence on the severity of the disease. This study examined the clinical spectrum and outcome of patients monitored in COVID-19 care centres (CCCs) in two West-African countries. METHODS: Burkina Faso and Guinea set up referral CCCs to hospitalise all symptomatic SARS-CoV-2 carriers, regardless of the severity of their symptoms. Data collected from hospitalised patients by November 2020 are presented. RESULT: A total of 1,805 patients (64% men, median age 41 years) were admitted with COVID-19. Symptoms lasted for a median of 7 days (IQR 4-11). During hospitalisation, 443 (25%) had a SpO2 < 94% at least once, 237 (13%) received oxygen and 266 (15%) took corticosteroids. Mortality was 5% overall, and 1%, 5% and 14% in patients aged <40, 40-59 and ≥60 years, respectively. In multivariable analysis, the risk of death was higher in men (aOR 2.0, 95% CI 1.1; 3.6), people aged ≥60 years (aOR 2.9, 95% CI 1.7; 4.8) and those with chronic hypertension (aOR 2.1, 95% CI 1.2; 3.4). CONCLUSION: COVID-19 is as severe in Africa as elsewhere, and there must be more vigilance for common risk factors such as older age and hypertension.< Réduire

Mots clés en anglais

SARS-Cov-2

COVID-19

Sub-Saharan Africa

Mortality

Comorbidities

URI

https://oskar-bordeaux.fr/handle/20.500.12278/106487

DOI

http://dx.doi.org/10.1016/j.ijid.2021.05.024

Unités de recherche

Bordeaux Population Health Research Center (BPH) - UMR 1219

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Clinical presentation, outcomes and factors associated with mortality: A prospective study from three COVID-19 referral care centres in West Africa

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