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Research priorities to inform "Treat All" policy implementation for people living with HIV in sub-Saharan Africa: a consensus statement from the International epidemiology Databases to Evaluate AIDS (IeDEA)

dc.rights.licenseopenen_US
dc.contributor.authorYOTEBIENG, M.
dc.contributor.authorBRAZIER, E.
dc.contributor.authorADDISON, D.
dc.contributor.authorKIMMEL, A. D.
dc.contributor.authorCORNELL, M.
dc.contributor.authorKEISER, O.
dc.contributor.authorPARCESEPE, A. M.
dc.contributor.authorONOVO, A.
dc.contributor.authorLANCASTER, K. E.
dc.contributor.authorCASTELNUOVO, B.
dc.contributor.authorMURNANE, P. M.
dc.contributor.authorCOHEN, C. R.
dc.contributor.authorVREEMAN, R. C.
dc.contributor.authorDAVIES, M. A.
dc.contributor.authorDUDA, S. N.
dc.contributor.authorYIANNOUTSOS, C. T.
dc.contributor.authorBONO, R. S.
dc.contributor.authorAGLER, R.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorBERNARD, Charlotte
dc.contributor.authorSYVERTSEN, J. L.
dc.contributor.authorSINAYOBYE, J. D.
dc.contributor.authorWIKRAMANAYAKE, R.
dc.contributor.authorSOHN, A. H.
dc.contributor.authorVON GROOTE, P. M.
dc.contributor.authorWANDELER, G.
dc.contributor.authorLEROY, V.
dc.contributor.authorWILLIAMS, C. F.
dc.contributor.authorWOOLS-KALOUSTIAN, K.
dc.contributor.authorNASH, D.
dc.date.accessioned2020-07-20T12:21:27Z
dc.date.available2020-07-20T12:21:27Z
dc.date.issued2019-01
dc.identifier.issn1758-2652en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/10532
dc.description.abstractEnINTRODUCTION: "Treat All" - the treatment of all people with HIV, irrespective of disease stage or CD4 cell count - represents a paradigm shift in HIV care that has the potential to end AIDS as a public health threat. With accelerating implementation of Treat All in sub-Saharan Africa (SSA), there is a need for a focused agenda and research to identify and inform strategies for promoting timely uptake of HIV treatment, retention in care, and sustained viral suppression and addressing bottlenecks impeding implementation. METHODS: The Delphi approach was used to develop consensus around research priorities for Treat All implementation in SSA. Through an iterative process (June 2017 to March 2018), a set of research priorities was collectively formulated and refined by a technical working group and shared for review, deliberation and prioritization by more than 200 researchers, implementation experts, policy/decision-makers, and HIV community representatives in East, Central, Southern and West Africa. RESULTS AND DISCUSSION: The process resulted in a list of nine research priorities for generating evidence to guide Treat All policies, implementation strategies and monitoring efforts. These priorities highlight the need for increased focus on adolescents, men, and those with mental health and substance use disorders - groups that remain underserved in SSA and for whom more effective testing, linkage and care strategies need to be identified. The priorities also reflect consensus on the need to: (1) generate accurate national and sub-national estimates of the size of key populations and describe those who remain underserved along the HIV-care continuum; (2) characterize the timeliness of HIV care and short- and long-term HIV care continuum outcomes, as well as factors influencing timely achievement of these outcomes; (3) estimate the incidence and prevalence of HIV-drug resistance and regimen switching; and (4) identify cost-effective and affordable service delivery models and strategies to optimize uptake and minimize gaps, disparities, and losses along the HIV-care continuum, particularly among underserved populations. CONCLUSIONS: Reflecting consensus among a broad group of experts, researchers, policy- and decision-makers, PLWH, and other stakeholders, the resulting research priorities highlight important evidence gaps that are relevant for ministries of health, funders, normative bodies and research networks.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/us/
dc.subject.enIDLIC
dc.title.enResearch priorities to inform "Treat All" policy implementation for people living with HIV in sub-Saharan Africa: a consensus statement from the International epidemiology Databases to Evaluate AIDS (IeDEA)
dc.title.alternativeJ Int AIDS Socen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1002/jia2.25218en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed30657644en_US
bordeaux.journalJournal of the International AIDS Societyen_US
bordeaux.pagee25218en_US
bordeaux.volume22en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.issue1en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-02902893
hal.version1
hal.date.transferred2020-07-20T12:21:34Z
hal.exporttrue
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