Pulmonary Tuberculosis and Management of Contact Patients in a Department of Nephrology and Kidney Transplantation
dc.rights.license | open | en_US |
dc.contributor.author | BURGUET, Laure | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | DUVIGNAUD, Alexandre | |
dc.contributor.author | NGUYEN, Duc | |
dc.contributor.author | RECEVEUR, Marie-Catherine | |
hal.structure.identifier | Immunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle [ImmunoConcept] | |
dc.contributor.author | KAMINSKI, Hannah | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | PELLEGRIN, Isabelle | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | ROGUES, Anne-Marie | |
dc.contributor.author | PEUCHANT, Olivia | |
dc.contributor.author | MOREAU, Karine | |
hal.structure.identifier | Immunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle [ImmunoConcept] | |
dc.contributor.author | MERVILLE, Pierre | |
hal.structure.identifier | Immunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle [ImmunoConcept] | |
dc.contributor.author | COUZI, Lionel | |
dc.date.accessioned | 2021-07-05T09:29:23Z | |
dc.date.available | 2021-07-05T09:29:23Z | |
dc.date.issued | 2022-04 | |
dc.identifier.issn | 1201-9712 | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/94969 | |
dc.description.abstractEn | OBJECTIVES: To describe the investigation, follow-up, management and outcomes in a cohort of chronic kidney disease and kidney transplant recipients exposed to a case of pulmonary tuberculosis. METHODS: Contacts were investigated following a concentric circles approach and followed-up according to their level of priority. In those with an evidence of latent tuberculous infection, treatment decision was based on the level of exposure, individual vulnerability, as well as the results of an interferon-gamma release assay. RESULTS: 130 patients with chronic kidney disease and 180 kidney transplant recipients were identified as contacts and followed-up over a two-year period.Only few vulnerable high-priority contacts received an anti-tuberculosis treatment, including the 2 (100%)highly exposed patients in circle 1, 11/78(14.1%)chronic kidney disease patients and 4/142 (2.8%) kidney transplant recipients in circle 2, and10/52 (19.2%) chronic kidney disease patients and 2/36 (5.6%) kidney transplant recipients in circle 3;all having a positive interferon-gamma release assay result. No incident case of tuberculosis disease occurred. CONCLUSIONS: These findings suggest that latent tuberculosis treatment, as recommended in European guidelines, might be reasonably avoided in vulnerable high-priority contacts of circle 2 with a negative interferon-gamma release assay in countries with low prevalence of tuberculosis. | |
dc.language.iso | EN | en_US |
dc.subject.en | Contacts | |
dc.subject.en | Tuberculosis | |
dc.subject.en | Interferon Gamma Release Assay | |
dc.subject.en | Therapy | |
dc.subject.en | Prophylaxis | |
dc.title.en | Pulmonary Tuberculosis and Management of Contact Patients in a Department of Nephrology and Kidney Transplantation | |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1016/j.ijid.2021.05.045 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
dc.identifier.pubmed | 34029706 | en_US |
bordeaux.journal | International Journal of Infectious Diseases | en_US |
bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.institution | INSERM | en_US |
bordeaux.team | IDLIC | en_US |
bordeaux.team | MORPH3Eus | en_US |
bordeaux.team | PharmacoEpi-Drugs | en_US |
bordeaux.team | AHEAD_BPH | |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | oui | en_US |
hal.identifier | hal-03277960 | |
hal.version | 1 | |
hal.date.transferred | 2021-07-05T09:29:28Z | |
hal.export | true | |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=International%20Journal%20of%20Infectious%20Diseases&rft.date=2022-04&rft.eissn=1201-9712&rft.issn=1201-9712&rft.au=BURGUET,%20Laure&DUVIGNAUD,%20Alexandre&NGUYEN,%20Duc&RECEVEUR,%20Marie-Catherine&KAMINSKI,%20Hannah&rft.genre=article |
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