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dc.rights.licenseopenen_US
dc.contributor.authorBOURDEAU, Manon
dc.contributor.authorGUIBERT, Nicolas
dc.contributor.authorFORT, Emmanuel
dc.contributor.authorBOULOGNE, Sebastien
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLAGARDE, Emmanuel
dc.contributor.authorCHARBOTEL, Barbara
dc.date.accessioned2021-07-05T09:08:01Z
dc.date.available2021-07-05T09:08:01Z
dc.date.issued2021-05-26
dc.identifier.issn0001-4575en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/94966
dc.description.abstractEnBACKGROUND: Whereas an increased risk of road traffic crashes has been highlighted as linked to some medicine consumptions, there is no available data on this risk according to the type of journey (private, commuting or mission). Drivers on occupational journey (commuting or mission) are likely to have different coping behaviors related to the use of medicines than drivers on private journey. The aim of our study was to investigate the association between exposure to ten classes of medicines and the risk of being responsible for a road traffic crash according to the type of journey (private, commuting or mission). METHODS: The data used came from three French national databases: the national police database of injurious crashes, the police reports and the national health care insurance database. A total of 179,269 drivers aged between 18 and 65 years old involved in an injurious crash in France between July 2005 and December 2015 were included in the analyses. Logistic regression models stratified by journey were used to estimate the Odds Ratios (OR) and 95 % confidence intervals (95 % CI), adjusted for potential confounding factors. RESULTS: Medicines exposure levels were generally lower for drivers during occupational journeys, the risk of being responsible for a road traffic crash seems to be higher on commuting or mission journeys than on private journeys for four medicines. Indeed, for antiepileptics the OR was 1.59 [1.01-2.51] for mission journeys, 1.63 [1.24-2.15] for commuting journeys, and 1.47 [1.25-1.73] for private journey. For psycholeptics the OR was 1.02 [0.80-1.28] for mission journey, 1.19 [1.03-1.39] for commuting and 1.17 [1.08-1.26] for private journey. For psychoanaleptics OR was 1.35 [1.02-1.78] for mission journeys, 1.37 [1.17-1.60] for commuting journeys and 1.26 [1.14-1.40] for private journeys. Finally, for other nervous system drugs OR reached 2.04 [1.35-3.07] for mission journeys compared to 1.43 [1.21-1.70] for private journeys. CONCLUSION: Our results encourage the implementation of preventive measures about some treatments and diseases in the context of occupational journeys.
dc.language.isoENen_US
dc.subject.enRoad safety
dc.subject.enResponsibility analysis
dc.subject.enRoad traffic crash
dc.subject.enProfessional drivers
dc.subject.enMedicines
dc.title.enMedicine consumptions and occupational road risk
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.aap.2021.106202en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed34051434en_US
bordeaux.journalAccident Analysis and Preventionen_US
bordeaux.page106202en_US
bordeaux.volume158en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamIETOen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03277938
hal.version1
hal.date.transferred2021-07-05T09:08:05Z
hal.exporttrue
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