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Occupational exposures and incidence of chronic bronchitis and related symptoms over two decades: the European Community Respiratory Health Survey

dc.rights.licenseopenen_US
dc.contributor.authorLYTRAS, T.
dc.contributor.authorKOGEVINAS, M.
dc.contributor.authorKROMHOUT, H.
dc.contributor.authorCARSIN, A. E.
dc.contributor.authorANTO, J. M.
dc.contributor.authorBENTOUHAMI, H.
dc.contributor.authorWEYLER, J.
dc.contributor.authorHEINRICH, J.
dc.contributor.authorNOWAK, D.
dc.contributor.authorURRUTIA, I.
dc.contributor.authorMARTINEZ-MORATALLA, J.
dc.contributor.authorGULLON, J. A.
dc.contributor.authorVEGA, A. P.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorRAHERISON-SEMJEN, Chantal
dc.contributor.authorPIN, I.
dc.contributor.authorDEMOLY, P.
dc.contributor.authorLEYNAERT, B.
dc.contributor.authorVILLANI, S.
dc.contributor.authorGISLASON, T.
dc.contributor.authorSVANES, O.
dc.contributor.authorHOLM, M.
dc.contributor.authorFORSBERG, B.
dc.contributor.authorNORBACK, D.
dc.contributor.authorMEHTA, A. J.
dc.contributor.authorPROBST-HENSCH, N.
dc.contributor.authorBENKE, G.
dc.contributor.authorJOGI, R.
dc.contributor.authorTOREN, K.
dc.contributor.authorSIGSGAARD, T.
dc.contributor.authorSCHLUNSSEN, V.
dc.contributor.authorOLIVIERI, M.
dc.contributor.authorBLANC, P. D.
dc.contributor.authorWATKINS, J.
dc.contributor.authorBONO, R.
dc.contributor.authorBUIST, A. S.
dc.contributor.authorVERMEULEN, R.
dc.contributor.authorJARVIS, D.
dc.contributor.authorZOCK, J. P.
dc.date.accessioned2020-06-29T07:39:06Z
dc.date.available2020-06-29T07:39:06Z
dc.date.issued2019-04
dc.identifier.issn1470-7926 (Electronic) 1351-0711 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/8251
dc.description.abstractEnOBJECTIVES: Chronic bronchitis (CB) is an important chronic obstructive pulmonary disease (COPD)-related phenotype, with distinct clinical features and prognostic implications. Occupational exposures have been previously associated with increased risk of CB but few studies have examined this association prospectively using objective exposure assessment. We examined the effect of occupational exposures on CB incidence in the European Community Respiratory Health Survey. METHODS: Population samples aged 20-44 were randomly selected in 1991-1993, and followed up twice over 20 years. Participants without chronic cough or phlegm at baseline were analysed. Coded job histories during follow-up were linked to the ALOHA Job Exposure Matrix, generating occupational exposure estimates to 12 categories of chemical agents. Their association with CB incidence over both follow-ups was examined with Poisson models using generalised estimating equations. RESULTS: 8794 participants fulfilled the inclusion criteria, contributing 13 185 observations. Only participants exposed to metals had a higher incidence of CB (relative risk (RR) 1.70, 95% CI 1.16 to 2.50) compared with non-exposed to metals. Mineral dust exposure increased the incidence of chronic phlegm (RR 1.72, 95% CI 1.43 to 2.06). Incidence of chronic phlegm was increased in men exposed to gases/fumes and to solvents and in women exposed to pesticides. CONCLUSIONS: Occupational exposures are associated with chronic phlegm and CB, and the evidence is strongest for metals and mineral dust exposure. The observed differences between men and women warrant further investigation.
dc.language.isoENen_US
dc.subject.enEPICENE
dc.title.enOccupational exposures and incidence of chronic bronchitis and related symptoms over two decades: the European Community Respiratory Health Survey
dc.title.alternativeOccup Environ Meden_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1136/oemed-2018-105274en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed30700596en_US
bordeaux.journalOccupational and Environmental Medicineen_US
bordeaux.page222-229en_US
bordeaux.volume76en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue4en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamEPICENE_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
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