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dc.rights.licenseopenen_US
dc.contributor.authorCHAMBORD, Jeremy
dc.contributor.authorCOUZI, Lionel
dc.contributor.authorMERVILLE, Pierre
dc.contributor.authorMOREAU, Karine
hal.structure.identifierBiologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases
dc.contributor.authorXUEREB, Fabien
hal.structure.identifierBiologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases
dc.contributor.authorDJABAROUTI, Sarah
dc.date.accessioned2021-06-24T14:49:29Z
dc.date.available2021-06-24T14:49:29Z
dc.date.issued2021-01-01
dc.identifier.issn2040-6223en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/79292
dc.description.abstractEnTo assess the effect of a pharmacist-led intervention, using Barrows cards method, during the first year after renal transplantation, on patient knowledge about their treatment, medication adherence and exposure to treatment in a French cohort. We conducted a before-and-after comparative study between two groups of patients: those who benefited from a complementary pharmacist-led intervention [intervention group (IG),  = 44] those who did not [control group (CG),  = 48]. The pharmacist-led intervention consisted of a behavioral and educational interview at the first visit (visit 1). The intervention was assessed 4 months later at the second visit (visit 2), using the following endpoints: treatment knowledge, medication adherence [proportion of days covered (PDC) by immunosuppressive therapy] and tacrolimus exposure. At visit 2, IG patients achieved a significantly higher knowledge score than CG patients (83.3% 72.2%,  = 0.001). We did not find any differences in treatment exposure or medication adherence; however, the intervention tended to reduce the proportion of non-adherent patients with low knowledge scores. Using the PDC by immunosuppressive therapy, we identified 10 non-adherent patients (10.9%) at visit 1 and six at visit 2. Our intervention showed a positive effect on patient knowledge about their treatment. However, our results did not show any improvement in overall medication adherence, which was likely to be because of the initially high level of adherence in our study population. Nevertheless, the intervention appears to have improved adherence in non-adherent patients with low knowledge scores.
dc.language.isoENen_US
dc.subject.enBarrows cards
dc.subject.enRenal transplantation
dc.subject.enadherence
dc.subject.enknowledge improvement
dc.subject.enpharmacist-led intervention
dc.title.enBenefit of a pharmacist-led intervention for medication management of renal transplant patients: a controlled before-and-after study.
dc.title.alternativeTher Adv Chronic Disen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1177/20406223211005275en_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologieen_US
dc.identifier.pubmed33868624en_US
bordeaux.journalTherapeutic Advances in Chronic Diseaseen_US
bordeaux.page20406223211005275en_US
bordeaux.volume12en_US
bordeaux.hal.laboratoriesBiologie des maladies cardiovasculaires (BMC) - UMR 1034en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.identifierhal-03270361
hal.version1
hal.date.transferred2021-06-24T14:49:32Z
hal.exporttrue
workflow.import.sourcepubmed
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