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dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorCLAIRON, Quentin
dc.contributor.authorBRUNEL, Nicolas J. B.
dc.date.accessioned2020-06-12T09:57:27Z
dc.date.available2020-06-12T09:57:27Z
dc.date.issued2019-03
dc.identifier.issn0378-3758en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/7906
dc.description.abstractEnWe address the problem of parameter estimation for partially observed linear Ordinary Differential Equations. Estimation from time series with standard estimators can give misleading results because estimation is often ill-posed, or the models are misspecified. The addition of a forcing function u, that represents uncertainties in the original ODE, can overcome these problems as shown in Clairon and Brunel (2017). A general regularized estimation procedure is derived, that corresponds to an Optimal Control Problem (OCP) solved by the Pontryagin Maximum Principle for nonlinear ODEs. Here, we focus on the linear case and solve the OCP with a computationally fast deterministic Kalman filter which allows weakening of conditions needed for root n-consistency. A significant improvement is the avoidance of the estimation of initial conditions thanks to a profiling step. Consequently, we can deal with more elaborated penalties and also provide a profiled semiparametric estimation procedure in the case of time-varying parameters. Simulations and real data examples show that our approach is generally more accurate and more reliable than reference methods when the Fisher information matrix is badly-conditioned, with noticeable improvement in the case of model misspecification. (C) 2018 Elsevier B.V. All rights reserved.
dc.language.isoENen_US
dc.subject.enSISTM
dc.title.enTracking for parameter and state estimation in possibly misspecified partially observed linear Ordinary Differential Equations
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.jspi.2018.06.005en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
bordeaux.journalJournal of Statistical Planning and Inferenceen_US
bordeaux.page188-206en_US
bordeaux.volume199en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamSISTM_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03212218
hal.version1
hal.date.transferred2021-04-30T01:49:44Z
hal.exporttrue
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