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Cardiovascular risk factors and near visual impairment among Congolese older people: EPIDEMCA-FU population-based cohort

dc.rights.licenseopenen_US
dc.contributor.authorGBESSEMEHLAN, Antoine
ORCID: 0000-0002-0725-8253
IDREF: 259906425
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorHELMER, Catherine
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDELCOURT, Cecile
ORCID: 0000-0002-2099-0481
IDREF: 035105291
dc.contributor.authorBOUMEDIENE, Farid
dc.contributor.authorNDAMBA-BANDZOUZI, Bebene
dc.contributor.authorM'BELESSO, Pascal
dc.contributor.authorSAMBA, Harielle
dc.contributor.authorKEHOUA, Gilles
dc.contributor.authorDESORMAIS, Ileana
dc.contributor.authorLACROIX, Philippe
dc.contributor.authorABOYANS, Victor
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDARTIGUES, Jean-Francois
ORCID: 0000-0001-9482-5529
IDREF: 058586105
dc.contributor.authorHOUINATO, Dismand
dc.contributor.authorPREUX, Pierre-Marie
dc.contributor.authorGUERCHET, Maelenn
dc.date.accessioned2021-05-06T13:58:36Z
dc.date.available2021-05-06T13:58:36Z
dc.date.issued2020
dc.date.conference2020-06-26
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/27177
dc.description.abstractEnObjective:It is recognized that some cardiovascular risk factors (CVRF) are involved in poor ocular health. The deleterious effects are potentially more pronounced among older adults. However, it is unknown whether CVRF areassociated independently or not to Visual Impairment (VI) among African older people while both (CVRF and VI) are verycommon in sub-Saharan Africa. Therefore, we investigated the association between CVRF and near VI amongCongolese older people.Methods: Participants were Congolese older people aged ≥ 65 years included in EPIDEMCA-FU (Epidemiology ofDementia in Central Africa - Follow-up) population-based cohort carried out from 2011 to 2015. Visual acuity wasassessed at 30 cm using a Parinaud chart. Near VI was defined as having a visual acuity < 20/40. A cohort design wasused taking all CVRF and covariates at baseline and visual acuity at 1st follow-up. Associations were investigated usingmultivariate logistic regression.Results: 549 participants were included in our analyses. Participants median age was 72 years [interquartile range: 68-78 years] and 331 (60.3%) were females. In total, 378 had near VI (328 had mild/moderate near VI, 38 had severe VI and12 were blind). Prevalence of near VI was 68.8% [95% Confidence Interval: 64.9% - 72.7%] and higher in males (71.1%;95%CI: 65.1% - 77.1%) than females (67.4%; 95% CI: 62.3% - 72.4%). Of the CVRF explored, we found that having highBMI ≥ 25 kg/m2 (adjusted Odds Ratio = 2.31 [95%CI: 1.25 – 4.28]), diabetes (aOR=2.14 [95%CI: 1.07 – 4.29]) andhypertension (aOR=1.65 [95%CI: 1.03 – 2.66]) were independently associated with near VI. However, after adjustmenton cognitive status, hypertension (full-adjusted OR=1.58 [95%CI: 0.97 – 2.58]) was no longer significantly associated withVI. There was no interaction between these CVRF. We found no significant association for alcohol consumption(p=0.541), smoking status (p=0.88), and indirect marker of poor diet (0.33) in our sample.Conclusion: Prevalence of near VI was high among Congolese older people. High BMI, diabetes, and hypertension wereindependently associated to near VI in this population. Our study suggests that these CVRF could represent targets for VIprevention. However, further studies are required to clarify underling mechanisms because these associations may bemediated by the presence of ocular conditions/eye diseases.
dc.language.isoENen_US
dc.title.enCardiovascular risk factors and near visual impairment among Congolese older people: EPIDEMCA-FU population-based cohort
dc.typeAutre communication scientifique (congrès sans actes - poster - séminaire...)en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.conference.title37th World Ophthalmology Congress (WOC2020 Virtual)en_US
bordeaux.countryzaen_US
bordeaux.title.proceeding37th World Ophthalmology Congress (WOC2020 Virtual)en_US
bordeaux.teamSEPIAen_US
bordeaux.conference.cityCape Townen_US
bordeaux.peerReviewedouien_US
bordeaux.import.sourcehal
hal.identifierhal-02944208
hal.version1
hal.exportfalse
workflow.import.sourcehal
bordeaux.COinSctx_ver=Z39.88-2004&amp;rft_val_fmt=info:ofi/fmt:kev:mtx:journal&amp;rft.date=2020&amp;rft.au=GBESSEMEHLAN,%20Antoine&amp;HELMER,%20Catherine&amp;DELCOURT,%20Cecile&amp;BOUMEDIENE,%20Farid&amp;NDAMBA-BANDZOUZI,%20Bebene&amp;rft.genre=conference


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