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Results in the ESPN/ERA-EDTA Registry suggest disparities in access to kidney transplantation but little variation in graft survival of children across Europe

dc.rights.licenseopenen_US
dc.contributor.authorBONTHUIS, M.
dc.contributor.authorCUPERUS, L.
dc.contributor.authorCHESNAYE, N. C.
dc.contributor.authorAKMAN, S.
dc.contributor.authorMELGAR, A. A.
dc.contributor.authorBAIKO, S.
dc.contributor.authorBOUTS, A. H.
dc.contributor.authorBOYER, O.
dc.contributor.authorDIMITROVA, K.
dc.contributor.authorCARMO, C. D.
dc.contributor.authorGRENDA, R.
dc.contributor.authorHEAF, J.
dc.contributor.authorJAHNUKAINEN, T.
dc.contributor.authorJANKAUSKIENE, A.
dc.contributor.authorKALTENEGGER, L.
dc.contributor.authorKOSTIC, M.
dc.contributor.authorMARKS, S. D.
dc.contributor.authorMITSIONI, A.
dc.contributor.authorNOVLJAN, G.
dc.contributor.authorPALSSON, R.
dc.contributor.authorPARVEX, P.
dc.contributor.authorPODRACKA, L.
dc.contributor.authorBJERRE, A.
dc.contributor.authorSEEMAN, T.
dc.contributor.authorSLAVICEK, J.
dc.contributor.authorSZABO, T.
dc.contributor.authorTÖNSHOFF, B.
dc.contributor.authorTORRES, D. D.
dc.contributor.authorVAN HOECK, K. J.
dc.contributor.authorLADFORS, S. W.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorHARAMBAT, Jerome
IDREF: 110567358
dc.contributor.authorGROOTHOFF, J. W.
dc.contributor.authorJAGER, K. J.
dc.date.accessioned2021-02-23T14:51:30Z
dc.date.available2021-02-23T14:51:30Z
dc.date.issued2020
dc.identifier.issn0085-2538en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/26328
dc.description.abstractEnOne of the main objectives of the European health policy framework is to ensure equitable access to high-quality health services across Europe. Here we examined country-specific kidney transplantation and graft failure rates in children and explore their country- and patient-level determinants. Patients under 20 years of age initiating kidney replacement therapy from January 2007 through December 2015 in 37 European countries participating in the ESPN/ERA-EDTA Registry were included in the analyses. Countries were categorized as low-, middle-, and high-income based on gross domestic product. At five years of follow-up, 4326 of 6909 children on kidney replacement therapy received their first kidney transplant. Overall median time from kidney replacement therapy start to first kidney transplantation was 1.4 (inter quartile range 0.3-4.3) years. The five-year kidney transplantation probability was 48.8% (95% confidence interval: 45.9-51.7%) in low-income, 76.3% (72.8-79.5%) in middle-income and 92.3% (91.0-93.4%) in high-income countries and was strongly associated with macro-economic factors. Gross domestic product alone explained 67% of the international variation in transplantation rates. Compared with high-income countries, kidney transplantation was 76% less likely to be performed in low-income and 58% less likely in middle-income countries. Overall five-year graft survival in Europe was 88% and showed little variation across countries. Thus, despite large disparities transplantation access across Europe, graft failure rates were relatively similar. Hence, graft survival in low-risk transplant recipients from lower-income countries seems as good as graft survival among all (low-, medium-, and high-risk) graft recipients from high-income countries.
dc.language.isoENen_US
dc.subjectLEHA
dc.title.enResults in the ESPN/ERA-EDTA Registry suggest disparities in access to kidney transplantation but little variation in graft survival of children across Europe
dc.title.alternativeKidney Inten_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.kint.2020.03.029en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
bordeaux.journalKidney Internationalen_US
bordeaux.page464-475en_US
bordeaux.volume98en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue2en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamLEHA_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03150204
hal.version1
hal.date.transferred2021-02-23T14:51:35Z
hal.exporttrue
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