Prevalence of hypercholesterolemia in Nigeria: a systematic review and meta-analysis
| dc.rights.license | open | en_US |
| dc.contributor.author | ADELOYE, D. | |
| dc.contributor.author | ABAA, D. Q. | |
| dc.contributor.author | OWOLABI, E. O. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | ALE, Boni Maxime | |
| dc.contributor.author | MPAZANJE, R. G. | |
| dc.contributor.author | DEWAN, M. T. | |
| dc.contributor.author | OMOYELE, C. | |
| dc.contributor.author | EZEIGWE, N. | |
| dc.contributor.author | ALEMU, W. | |
| dc.contributor.author | HARHAY, M. O. | |
| dc.contributor.author | AUTA, A. | |
| dc.contributor.author | ADEWOLE, I. F. | |
| dc.date.accessioned | 2021-01-12T14:30:58Z | |
| dc.date.available | 2021-01-12T14:30:58Z | |
| dc.date.issued | 2020 | |
| dc.identifier.issn | 0033-3506 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/23760 | |
| dc.description.abstractEn | ABSTRACT Objectives: Elevated blood cholesterol (hypercholesterolemia) is a significant cause of cardiovascular disease. We aimed to estimate national and zonal prevalence of hypercholesterolemia in Nigeria to help guide targeted public health programs. Design: This is a systematic review and synthesis of publicly available epidemiologic data on hypercholesterolemia in Nigeria. Methods: We systematically searched MEDLINE, EMBASE, Global Health, and Africa Journals Online for studies on the prevalence of hypercholesterolemia in Nigeria published between 1990 and 2018. We used a random-effects meta-analysis (Freeman-Tukey double arscine transformation) and meta-regression model to estimate the prevalence of hypercholesterolemia in Nigeria in 1995 and 2015. Results: 13 studies (n=16981) were retrieved. The pooled crude prevalence of hypercholesterolemia in Nigeria was 38% (95% CI: 26-51), with prevalence in women slightly higher (42%, 23-63) compared to men at (38%, 20-58). The prevalence was highest in the South-south (53%, 38-68) and lowest in the South-west (3%, 2-4) and North-east (4%, 2-7). Urban dwellers had a significantly higher rate (52%, 24-79) compared to rural dwellers (10%, 6-15). We estimated over 8.2 million persons (age-adjusted prevalence 16.5%) aged 20 years or more had hypercholesterolemia in Nigeria in 1995, increasing to 21.9 million persons (age-adjusted prevalence 25.9%) in 2015. Conclusions: Our findings suggest a high prevalence of hypercholesterolemia in Nigeria. Urbanization, lifestyles, diets, and culture appear to be driving an increasing prevalence, especially among women. Population-wide awareness and education on reducing elevated cholesterol levels and associated risks should be prioritised. | |
| dc.language.iso | EN | en_US |
| dc.title.en | Prevalence of hypercholesterolemia in Nigeria: a systematic review and meta-analysis | |
| dc.title.alternative | Public Health | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/j.puhe.2019.09.002 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| bordeaux.journal | Public health | en_US |
| bordeaux.page | 167-178 | en_US |
| bordeaux.volume | 178 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03107406 | |
| hal.version | 1 | |
| hal.date.transferred | 2021-01-12T14:31:03Z | |
| hal.export | true | |
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