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Fish Intake, Genetic Predisposition to Alzheimer Disease, and Decline in Global Cognition and Memory in 5 Cohorts of Older Persons
dc.rights.license | open | en_US |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | SAMIERI, Cecilia | |
dc.contributor.author | MORRIS, M. C. | |
dc.contributor.author | BENNETT, D. A. | |
dc.contributor.author | BERR, C. | |
dc.contributor.author | AMOUYEL, Philippe | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | DARTIGUES, Jean-Francois
ORCID: 0000-0001-9482-5529 IDREF: 058586105 | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | TZOURIO, Christophe
IDREF: 69829209 | |
dc.contributor.author | CHASMAN, D. I. | |
dc.contributor.author | GRODSTEIN, F. | |
dc.date.accessioned | 2021-01-04T15:16:55Z | |
dc.date.available | 2021-01-04T15:16:55Z | |
dc.date.issued | 2018-05-01 | |
dc.identifier.issn | 1476-6256 (Electronic) 0002-9262 (Linking) | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/23630 | |
dc.description.abstractEn | Fish are a primary source of long-chain omega-3 fatty acids, which may help delay cognitive aging. We pooled participants from the French Three-City study and four US cohorts (Nurses' Health Study, Women's Health Study, Chicago Health and Aging Project and Rush Memory and Aging Project) with diet and cognitive data (n = 23,688 Caucasians aged >/=65 years, 88% female, baseline year range, 1992-1999, median follow-up range, 3.9-9.1 years) to investigate the relation of fish intake to cognitive decline and examine interactions with Alzheimer's disease-related genes. We estimated cohort-specific associations between fish and change in composite scores of global cognition and episodic memory using linear mixed models, and pooled results using inverse-variance weighted meta-analysis. In multivariate analyses, higher fish intake was associated with slower decline in both global cognition and memory (P-trend </= 0.031). Consuming >/=4 versus <1 fish serving/week was associated with 0.018 (95% CI: 0.004, 0.032) standard units lower rate of memory decline; an effect estimate equivalent to that found for 4 years of age. For global cognition, no comparisons of higher versus low fish intake reached statistical significance. In this meta-analysis, increasing fish intake was associated with decreasing memory decline. We found no evidence of effect modification by Alzheimer's disease genes. | |
dc.language.iso | EN | en_US |
dc.subject.en | LEHA | |
dc.subject.en | SEPIA | |
dc.subject.en | VINTAGE | |
dc.title.en | Fish Intake, Genetic Predisposition to Alzheimer Disease, and Decline in Global Cognition and Memory in 5 Cohorts of Older Persons | |
dc.title.alternative | Am J Epidemiol | en_US |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1093/aje/kwx330 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
dc.identifier.pubmed | 29053784 | en_US |
bordeaux.journal | American journal of epidemiology | en_US |
bordeaux.page | 933-940 | en_US |
bordeaux.volume | 187 | en_US |
bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - U1219 | en_US |
bordeaux.issue | 5 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.team | LEHA_BPH | |
bordeaux.team | SEPIA | en_US |
bordeaux.team | VINTAGE | en_US |
bordeaux.team | HEALTHY_BPH | |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
hal.export | false | |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=American%20journal%20of%20epidemiology&rft.date=2018-05-01&rft.volume=187&rft.issue=5&rft.spage=933-940&rft.epage=933-940&rft.eissn=1476-6256%20(Electronic)%200002-9262%20(Linking)&rft.issn=1476-6256%20(Electronic)%200002-9262%20(Linking)&rft.au=SAMIERI,%20Cecilia&MORRIS,%20M.%20C.&BENNETT,%20D.%20A.&BERR,%20C.&AMOUYEL,%20Philippe&rft.genre=article |
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