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dc.rights.licenseopenen_US
dc.contributor.authorNATIVEL, M.
dc.contributor.authorPOTIER, L.
dc.contributor.authorALEXANDRE, L.
dc.contributor.authorBAILLET-BLANCO, L.
dc.contributor.authorDUCASSE, E.
dc.contributor.authorVELHO, G.
dc.contributor.authorMARRE, M.
dc.contributor.authorROUSSEL, R.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorRIGALLEAU, Vincent
IDREF: 069788146
dc.contributor.authorMOHAMMEDI, Kamel
dc.date.accessioned2020-12-08T15:35:01Z
dc.date.available2020-12-08T15:35:01Z
dc.date.issued2018-10-23
dc.identifier.issn1475-2840 (Electronic) 1475-2840 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/21373
dc.description.abstractEnLower-extremity arterial disease (LEAD) is a major endemic disease with an alarming increased prevalence worldwide. It is a common and severe condition with excess risk of major cardiovascular events and death. It also leads to a high rate of lower-limb adverse events and non-traumatic amputation. The American Diabetes Association recommends a widespread medical history and clinical examination to screen for LEAD. The ankle brachial index (ABI) is the first non-invasive tool recommended to diagnose LEAD although its variable performance in patients with diabetes. The performance of ABI is particularly affected by the presence of peripheral neuropathy, medial arterial calcification, and incompressible arteries. There is no strong evidence today to support an alternative test for LEAD diagnosis in these conditions. The management of LEAD requires a strict control of cardiovascular risk factors including diabetes, hypertension, and dyslipidaemia. The benefit of intensive versus standard glucose control on the risk of LEAD has not been clearly established. Antihypertensive, lipid-lowering, and antiplatelet agents are obviously worthfull to reduce major cardiovascular adverse events, but few randomised controlled trials (RCTs) have evaluated the benefits of these treatments in terms of LEAD and its related adverse events. Smoking cessation, physical activity, supervised walking rehabilitation and healthy diet are also crucial in LEAD management. Several advances have been achieved in endovascular and surgical revascularization procedures, with obvious improvement in LEAD management. The revascularization strategy should take into account several factors including anatomical localizations of lesions, medical history of each patients and operator experience. Further studies, especially RCTs, are needed to evaluate the interest of different therapeutic strategies on the occurrence and progression of LEAD and its related adverse events in patients with diabetes.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enLEHA
dc.title.enLower extremity arterial disease in patients with diabetes: a contemporary narrative review
dc.title.alternativeCardiovasc Diabetolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1186/s12933-018-0781-1en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed30352589en_US
bordeaux.journalCardiovascular Diabetologyen_US
bordeaux.page138en_US
bordeaux.volume17en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue1en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamLEHA_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03047019
hal.version1
hal.date.transferred2020-12-08T15:35:07Z
hal.exporttrue
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Cardiovascular%20Diabetology&rft.date=2018-10-23&rft.volume=17&rft.issue=1&rft.spage=138&rft.epage=138&rft.eissn=1475-2840%20(Electronic)%201475-2840%20(Linking)&rft.issn=1475-2840%20(Electronic)%201475-2840%20(Linking)&rft.au=NATIVEL,%20M.&POTIER,%20L.&ALEXANDRE,%20L.&BAILLET-BLANCO,%20L.&DUCASSE,%20E.&rft.genre=article


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