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Sex-specific association between neighborhood characteristics and dementia: The Three-City cohort

dc.rights.licenseopenen_US
dc.contributor.authorLETELLIER, N.
dc.contributor.authorGUTIERREZ, L. A.
dc.contributor.authorCARRIERE, I.
dc.contributor.authorGABELLE, A.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDARTIGUES, Jean-Francois
ORCID: 0000-0001-9482-5529
IDREF: 058586105
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDUFOUIL, Carole
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorHELMER, Catherine
dc.contributor.authorCADOT, E.
dc.contributor.authorBERR, C.
dc.date.accessioned2020-11-30T11:07:51Z
dc.date.available2020-11-30T11:07:51Z
dc.date.issued2018-04
dc.identifier.issn1552-5279 (Electronic) 1552-5260 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/21258
dc.description.abstractEnINTRODUCTION: The living environment affects general health and may influence cognitive aging; however, the relationships between neighborhood characteristics and dementia are still poorly understood. METHODS: We used data from a French population-based prospective study (the Three-City cohort) that included 7016 participants aged 65 years and older with a 12-year follow-up. We used principal components analysis of neighborhood composition indicators to construct the Three-City deprivation score. To study its impact on dementia incidence, we performed survival analyses using a marginal Cox model to take into account intraneighborhood correlations. As interaction with sex was significant, analyses were stratified by sex. RESULTS: Even after controlling on individual factors, women living in deprived neighborhoods were at higher risk of dementia (hazard ratio = 1.29, 95% confidence interval 1.00-1.67) and Alzheimer's disease (hazard ratio = 1.42, 95% confidence interval 1.09-1.84). No association was found for men. DISCUSSION: Living in a deprived neighborhood is associated with higher risk of dementia in women.
dc.language.isoENen_US
dc.subject.enLEHA
dc.subject.enSEPIA
dc.subject.enVINTAGE
dc.subject.en3C
dc.title.enSex-specific association between neighborhood characteristics and dementia: The Three-City cohort
dc.title.alternativeAlzheimers Dementen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.jalz.2017.09.015en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed29102501en_US
bordeaux.journalAlzheimer's & dementiaen_US
bordeaux.page473-482en_US
bordeaux.volume14en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue4en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamSEPIAen_US
bordeaux.teamLEHA_BPH
bordeaux.teamVINTAGEen_US
bordeaux.team3Cen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
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