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Mini-fluid Challenge of 100 ml of Crystalloid Predicts Fluid Responsiveness in the Operating Room.

dc.rights.licenseopenen_US
hal.structure.identifierBiologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases
dc.contributor.authorBIAIS, M.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDE COURSON DE LA VILLENEUVE, Hugues
dc.contributor.authorLANCHON, R.
dc.contributor.authorPEREIRA, B.
dc.contributor.authorBARDONNEAU, G.
dc.contributor.authorGRITON, M.
dc.contributor.authorSESAY, M.
dc.contributor.authorNOUETTE-GAULAIN, Karine
dc.date.accessioned2020
dc.date.available2020
dc.date.issued2017
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/20893
dc.description.abstractEnBACKGROUND: Mini-fluid challenge of 100 ml colloids is thought to predict the effects of larger amounts of fluid (500 ml) in intensive care units. This study sought to determine whether a low quantity of crystalloid (50 and 100 ml) could predict the effects of 250 ml crystalloid in mechanically ventilated patients in the operating room. METHODS: A total of 44 mechanically ventilated patients undergoing neurosurgery were included. Volume expansion (250 ml saline 0.9%) was given to maximize cardiac output during surgery. Stroke volume index (monitored using pulse contour analysis) and pulse pressure variations were recorded before and after 50 ml infusion (given for 1 min), after another 50 ml infusion (given for 1 min), and finally after 150 ml infusion (total = 250 ml). Changes in stroke volume index induced by 50, 100, and 250 ml were recorded. Positive fluid challenges were defined as an increase in stroke volume index of 10% or more from baseline after 250 ml. RESULTS: A total of 88 fluid challenges were performed (32% of positive fluid challenges). Changes in stroke volume index induced by 100 ml greater than 6% (gray zone between 4 and 7%, including 19% of patients) predicted fluid responsiveness with a sensitivity of 93% (95% CI, 77 to 99%) and a specificity of 85% (95% CI, 73 to 93%). The area under the receiver operating curve of changes in stroke volume index induced by 100 ml was 0.95 (95% CI, 0.90 to 0.99) and was higher than those of changes in stroke volume index induced by 50 ml (0.83 [95% CI, 0.75 to 0.92]; P = 0.01) and pulse pressure variations (0.65 [95% CI, 0.53 to 0.78]; P \textless 0.005). CONCLUSIONS: Changes in stroke volume index induced by rapid infusion of 100 ml crystalloid predicted the effects of 250 ml crystalloid in patients ventilated mechanically in the operating room.
dc.language.isoENen_US
dc.subject*Article CLINIQUE
dc.title.enMini-fluid Challenge of 100 ml of Crystalloid Predicts Fluid Responsiveness in the Operating Room.
dc.typeArticle de revueen_US
dc.identifier.doi10.1097/ALN.0000000000001753en_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologieen_US
bordeaux.journalAnesthesiologyen_US
bordeaux.page450–456en_US
bordeaux.volume127en_US
bordeaux.hal.laboratoriesBiologie des maladies cardiovasculaires - U1034en_US
bordeaux.issue3en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERM
bordeaux.teamBIOSTAT_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Anesthesiology&rft.date=2017&rft.volume=127&rft.issue=3&rft.spage=450%E2%80%93456&rft.epage=450%E2%80%93456&rft.au=BIAIS,%20M.&DE%20COURSON%20DE%20LA%20VILLENEUVE,%20Hugues&LANCHON,%20R.&PEREIRA,%20B.&BARDONNEAU,%20G.&rft.genre=article


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