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Predictors of driving risk in patients with obstructive sleep apnea syndrome treated by continuous positive airway pressure: a French multicenter prospective cohort

dc.rights.licenseopenen_US
hal.structure.identifierSommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY]
dc.contributor.authorCOELHO, Julien
dc.contributor.authorBAILLY, Sébastien
dc.contributor.authorBAILLIEUL, Sébastien
dc.contributor.authorSAGASPE, Patricia
dc.contributor.authorMCNICHOLAS, Walter T
hal.structure.identifierSommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY]
dc.contributor.authorTAILLARD, Jacques
hal.structure.identifierSommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY]
dc.contributor.authorMICOULAUD-FRANCHI, Jean-Arthur
dc.contributor.authorSAPÈNE, Marc
dc.contributor.authorGRILLET, Yves
dc.contributor.authorTAMISIER, Renaud
dc.contributor.authorPÉPIN, Jean-Louis
hal.structure.identifierSommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY]
dc.contributor.authorPHILIP, Pierre
dc.date.accessioned2025-09-01T14:19:44Z
dc.date.available2025-09-01T14:19:44Z
dc.date.issued2024-09-25
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/207550
dc.description.abstractEnStudy objectives: To investigate the predictors of persistent driving risk related to sleepiness in patients with obstructive sleep apnea syndrome (OSAS) treated by continuous positive airway pressure (CPAP). Methods: Longitudinal analysis of a prospective national database including 5308 patients with OSAS and an indication of CPAP. Near misses related to sleepiness, accidents related to sleepiness, and sleepiness at the wheel (SAW) were assessed before initiation and after ≥90 days of treatment. Multivariable associations with the cumulative incidence of near-misses and accidents under treatment were calculated using Cox models adjusted for age, sex, obesity, sleep duration, SAW, accidents/near-misses history, depressive symptoms, residual apnea-hypopnea index, and adherence to treatment. Results: Residual SAW under treatment was associated with an eight-fold higher incidence of near-misses related to sleepiness (hazard ratios [HR] = 8.63 [6.08-12.2]) and five-fold higher incidence of accidents related to sleepiness (HR = 5.24 [2.81-9.78]). Adherence ≤4 h/night was also a significant predictor of persistent driving risk (HR = 1.74 [1.12-2.71] for near-misses and HR = 3.20 [1.37-7.49] for accidents). Conclusions: Residual SAW and treatment adherence ≤4 h/night are easy-to-assess markers to detect persistent driving risk during the follow-up evaluations of patients under treatment. Health professionals, but also policymakers, should be aware of the crucial importance of systematically evaluating these elements during the follow-up evaluations of the patients with OSAS treated by CPAP to better evaluate their driving risk.
dc.language.isoENen_US
dc.subject.enContinuous positive airway pressure
dc.subject.enExcessive daytime sleepiness
dc.subject.enObstructive sleep apnea syndrome
dc.subject.enTraffic accident
dc.title.enPredictors of driving risk in patients with obstructive sleep apnea syndrome treated by continuous positive airway pressure: a French multicenter prospective cohort
dc.title.alternativeSleepen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1093/sleep/zsae211en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed39319690en_US
bordeaux.journalSLEEPen_US
bordeaux.volume47en_US
bordeaux.hal.laboratoriesSANPSY (Sommeil, Addiction, Neuropsychiatrie) - UMR 6033en_US
bordeaux.issue11en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcecrossref
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcecrossref
dc.rights.ccPas de Licence CCen_US
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