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Imaging-Aided VT Ablation. Long-Term Results From a Pilot Study

dc.rights.licenseopenen_US
dc.contributor.authorSACRISTAN, Benjamin
dc.contributor.authorCOCHET, Hubert
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorBOUYER, Benjamin
dc.contributor.authorTIXIER, Romain
dc.contributor.authorDUCHATEAU, Josselin
dc.contributor.authorDERVAL, Nicolas
dc.contributor.authorPAMBRUN, Thomas
dc.contributor.authorARNAUD, Marine
dc.contributor.authorCHARTON, Jan
dc.contributor.authorDITAC, Geoffroy
dc.contributor.authorPLANT, Allan
dc.contributor.authorFITZGERALD, John
dc.contributor.authorSDIRI-CHENITI, Soumaya
dc.contributor.authorVERHAEGE, Laurens
dc.contributor.authorMONTAUDON, Michel
dc.contributor.authorHOCINI, Meleze
dc.contributor.authorHAISSAGUERRE, Michel
dc.contributor.authorSERMESANT, Maxime
dc.contributor.authorJAIS, Pierre
dc.contributor.authorSACHER, Frederic
dc.date.accessioned2025-07-08T08:33:27Z
dc.date.available2025-07-08T08:33:27Z
dc.date.issued2025-05-26
dc.identifier.issn1045-3873en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/207257
dc.description.abstractEnBackground: Ventricular tachycardia (VT) ablation has become a cornerstone of patient care, especially for post-MI VT. Several strategies have proven effective for achieving rhythm control in this population, but the workflow is highly variable and depends on the physician's experience. Aim: This study describes the initial systematic experience of VT ablation targeting wall thickness heterogeneity on a cardiac computed tomography (CT) scanner used as a surrogate for mapped VT isthmii. Methods: Consecutive patients with post-MI VT, a CT scan, and a first VT ablation were included from January 2017 to May 2022. Targets were identified based on wall thickness heterogeneity. After image integration, ablation with > 10 grams, 40-50 W was performed with the aim of blocking the CT channels/render them non-capturable. Only then was inducibility tested. Inducible VT, if any, were conventionally mapped and ablated with the aim of reaching non-inducibility. Results: Thirty-nine patients (97.4% male, age: mean LVEF 35 +/- 10%) were included. The mean number of identified CT Channels was 3.6 +/- 1.8/patient. Non-inducibility was achieved in 19 (48.7%) of patients after initial imaging-guided ablation, while at least one VT could be induced in 19 (48.7%). Among these patients, 4 had VT related to unblocked or reconnected CT-determined VT channels, and 15 from other areas (border zone), typically with faster cycle length. After further mapping and ablation, 3 (7.7%) patients remained inducible. Mean radiofrequency time was 35 +/- 19 min for CT Channels ablation, with an additional 11 +/- 8 min for supplementary ablation (global mean RF time 35 +/- 19 min). With a mean follow-up of 47.8 +/- 24.3 months, 61.9% (95% CI: 44.0%-75.5%) remained VT free. Conclusion: CT-guided ablation represents a feasible and safe strategy for VT ablation in patients with an ischemic cardiomyopathy.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enCT‐Scan
dc.subject.enInheart Software
dc.subject.enCatheter Ablation
dc.subject.enImaging
dc.subject.enVentricular Tachycardia
dc.title.enImaging-Aided VT Ablation. Long-Term Results From a Pilot Study
dc.title.alternativeJ Cardiovasc Electrophysiolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1111/jce.16741en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed40420538en_US
bordeaux.journalJournal of Cardiovascular Electrophysiologyen_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamAHEAD_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-05150007
hal.version1
hal.date.transferred2025-07-08T08:33:31Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20Cardiovascular%20Electrophysiology&rft.date=2025-05-26&rft.eissn=1045-3873&rft.issn=1045-3873&rft.au=SACRISTAN,%20Benjamin&COCHET,%20Hubert&BOUYER,%20Benjamin&TIXIER,%20Romain&DUCHATEAU,%20Josselin&rft.genre=article


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