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Cardiogenic shock and chronic kidney disease: Dangerous liaisons

dc.rights.licenseopenen_US
hal.structure.identifierInstitut des Maladies Métaboliques et Casdiovasculaires [UPS/Inserm U1297 - I2MC]
hal.structure.identifierCentre Hospitalier Universitaire de Toulouse [CHU Toulouse]
dc.contributor.authorCHERBI, Miloud
hal.structure.identifierCentre Hospitalier Lyon Sud [CHU - HCL] [CHLS]
dc.contributor.authorBONNEFOY, Eric
hal.structure.identifierHôpital Européen Georges Pompidou [APHP] [HEGP]
dc.contributor.authorPUYMIRAT, Etienne
hal.structure.identifierFacteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
hal.structure.identifierCentre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
dc.contributor.authorLAMBLIN, Nicolas
hal.structure.identifierCentre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
hal.structure.identifierHôpital Haut-Lévêque [CHU Bordeaux]
dc.contributor.authorGERBAUD, Edouard
hal.structure.identifierHôpital Nord [CHU - APHM]
hal.structure.identifierMediterranean Association for Research and Studies in Cardiology [MARS cardio]
dc.contributor.authorBONELLO, Laurent
hal.structure.identifierCentre Hospitalier Régional Universitaire de Nancy [CHRU Nancy]
dc.contributor.authorLEVY, Bruno
hal.structure.identifierInstitut Mondor de Recherche Biomédicale [IMRB]
hal.structure.identifierHôpital Henri Mondor
dc.contributor.authorLIM, Pascal
hal.structure.identifierCH de Saint-Malo [Broussais]
dc.contributor.authorMULLER, Laura
hal.structure.identifierNouvel Hôpital Civil de Strasbourg
hal.structure.identifierCentre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
dc.contributor.authorMERDJI, Hamid
hal.structure.identifierHôpital Louis Pasteur [Chartres]
dc.contributor.authorRANGE, Grégoire
hal.structure.identifierCentre Hospitalier Universitaire de Nice [CHU Nice]
dc.contributor.authorFERRARI, Emile
hal.structure.identifierInstitut des Maladies Métaboliques et Casdiovasculaires [UPS/Inserm U1297 - I2MC]
hal.structure.identifierCentre Hospitalier Universitaire de Toulouse [CHU Toulouse]
dc.contributor.authorELBAZ, Meyer
hal.structure.identifierCentre Hospitalier d'Aix en Provence [Aix-en-Provence] [CHIAP ]
dc.contributor.authorKHACHAB, Hadi
hal.structure.identifierHôpital de la Timone [CHU - APHM] [TIMONE]
hal.structure.identifierAix Marseille Université [AMU]
dc.contributor.authorBOURENNE, Jeremy
hal.structure.identifierCentre Hospitalier Régional Universitaire de Besançon [CHRU Besançon]
dc.contributor.authorSERONDE, Marie-France
hal.structure.identifierCentre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
dc.contributor.authorFLORENS, Nans
hal.structure.identifierCentre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
hal.structure.identifierFacteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
dc.contributor.authorSCHURTZ, Guillaume
hal.structure.identifierCHU Tenon [AP-HP]
dc.contributor.authorLABBÉ, Vincent
hal.structure.identifierCentre de Recherche en Acquisition et Traitement de l'Image pour la Santé [CREATIS]
hal.structure.identifierHôpital de la Croix-Rousse [CHU - HCL]
hal.structure.identifierCentre Hospitalier Lyon Sud [CHU - HCL] [CHLS]
dc.contributor.authorHARBAOUI, Brahim
hal.structure.identifierCentre Hospitalier Universitaire [CHU Grenoble] [CHUGA]
dc.contributor.authorVANZETTO, Gerald
hal.structure.identifierCHU Clermont-Ferrand
hal.structure.identifierUniversité Clermont Auvergne [UCA]
dc.contributor.authorCOMBARET, Nicolas
hal.structure.identifierNouvel Hôpital Civil de Strasbourg
hal.structure.identifierCentre Hospitalier Universitaire [Strasbourg] [CHU Strasbourg]
dc.contributor.authorMARCHANDOT, Benjamin
hal.structure.identifierCentre Hospitalier Universitaire de Nîmes [CHU Nîmes]
hal.structure.identifierUniversité de Montpellier [UM]
dc.contributor.authorLATTUCA, Benoit
hal.structure.identifierLaboratoire Traitement du Signal et de l'Image [LTSI]
hal.structure.identifierCentre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
dc.contributor.authorLEURENT, Guillaume
hal.structure.identifierInstitut des Maladies Métaboliques et Casdiovasculaires [UPS/Inserm U1297 - I2MC]
hal.structure.identifierCentre Hospitalier Universitaire de Toulouse [CHU Toulouse]
dc.contributor.authorFAGUER, Stanislas
hal.structure.identifierPhysiologie & médecine expérimentale du Cœur et des Muscles [U 1046] [PhyMedExp]
hal.structure.identifierCentre Hospitalier Régional Universitaire [Montpellier] [CHRU Montpellier]
dc.contributor.authorROUBILLE, François
hal.structure.identifierInstitut des Maladies Métaboliques et Casdiovasculaires [UPS/Inserm U1297 - I2MC]
hal.structure.identifierCentre Hospitalier Universitaire de Toulouse [CHU Toulouse]
dc.contributor.authorDELMAS, Clément
dc.date.accessioned2025-06-16T12:34:23Z
dc.date.available2025-06-16T12:34:23Z
dc.date.issued2024-03-01
dc.identifier.issn1875-2136en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/206923
dc.description.abstractEnBackground: Chronic kidney disease (CKD) is one of the leading causes of death worldwide, closely interrelated with cardiovascular diseases, ultimately leading to the failure of both organs - the so-called "cardiorenal syndrome". Despite this burden, data related to cardiogenic shock outcomes in CKD patients are scarce.Methods: FRENSHOCK (NCT02703038) was a prospective registry involving 772 patients with cardiogenic shock from 49 centres. One-year outcomes (rehospitalization, death, heart transplantation, ventricular assist device) were analysed according to history of CKD at admission and were adjusted on independent predictive factors.Results: CKD was present in 164 of 771 patients (21.3%) with cardiogenic shock; these patients were older (72.7 vs. 63.9years) and had more comorbidities than those without CKD. CKD was associated with a higher rate of all-cause mortality at 1month (36.6% vs. 23.2%; hazard ratio 1.39, 95% confidence interval 1.01-1.9; P=0.04) and 1year (62.8% vs. 40.5%, hazard ratio 1.39, 95% confidence interval 1.09-1.77; P<0.01). Patients with CKD were less likely to be treated with norepinephrine/epinephrine or undergo invasive ventilation or receive mechanical circulatory support, but were more likely to receive renal replacement therapy (RRT). RRT was associated with a higher risk of all-cause death at 1month and 1year regardless of baseline CKD status.Conclusions: Cardiogenic shock and CKD are frequent "cross-talking" conditions with limited therapeutic options, resulting in higher rates of death at 1month and 1year. RRT is a strong predictor of death, regardless of preexisting CKD. Multidisciplinary teams involving cardiac and kidney physicians are required to provide integrated care for patients with failure of both organs.
dc.language.isoENen_US
dc.rights.urihttp://creativecommons.org/licenses/by/
dc.subject.enCardiogenic shock
dc.subject.enChronic kidney disease
dc.subject.enEpidemiology
dc.subject.enMortality
dc.subject.enPrognosis
dc.title.enCardiogenic shock and chronic kidney disease: Dangerous liaisons
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.acvd.2024.01.006en_US
dc.subject.halSciences du Vivant [q-bio]/Ingénierie biomédicaleen_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologie/Cardiologie et système cardiovasculaireen_US
bordeaux.journalArchives of cardiovascular diseasesen_US
bordeaux.page255-265en_US
bordeaux.volume117en_US
bordeaux.hal.laboratoriesCentre de Recherche Cardio-Thoracique de Bordeaux (CRCTB) - U1045en_US
bordeaux.issue4en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-04544818
hal.version1
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccPas de Licence CCen_US
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