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Responsive micelles and vesicles based on polypeptide diblock copolymers

dc.rights.licenseopen
hal.structure.identifierLaboratoire de Chimie des polymères organiques [LCPO]
dc.contributor.authorCHÉCOT, Frédéric
hal.structure.identifierLaboratoire de Chimie des polymères organiques [LCPO]
hal.structure.identifierTeam 1 LCPO : Polymerization Catalyses & Engineering
dc.contributor.authorRODRIGUEZ-HERNANDEZ, Juan
hal.structure.identifierLaboratoire de Chimie des polymères organiques [LCPO]
hal.structure.identifierTeam 1 LCPO : Polymerization Catalyses & Engineering
dc.contributor.authorGNANOU, Yves
hal.structure.identifierLaboratoire de Chimie des polymères organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorLECOMMANDOUX, Sebastien
dc.date.accessioned2020
dc.date.available2020
dc.date.issued2006
dc.identifier.issn1042-7147
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/20658
dc.description.abstractEnThe self-assembly of well-defined polypeptide-based diblock copolymers into micelles and vesicles is presented. The stimuli-responsive behavior of polypeptides to pH and ionic strength is used to produce stimuli-responsive nanoparticles with a control size and shape. Results focusing on vesicles obtained from polypeptide-based diblock copolymers that are particularly promising for biomedical application will be detailed by means of static and dynamic light scattering analysis, UV circular dichroism, NMR and small angle neutron scattering experiments. Also systems that are able to form vesicles with narrow size distributions at basic and acidic pH going through an intermediate state of single polymer chains are presented. These nanoparticles are particularly interesting for encapsulation and delivery purposes at a controlled pH. Finally, surface self-assembly of micelles and vesicles will be shown as models for biological surfaces such as mucosal surfaces.
dc.language.isoen
dc.publisherWiley
dc.subject.enresponsive
dc.subject.envesicles
dc.subject.enpolypeptide
dc.subject.enblock copolymers
dc.subject.enself-assembly
dc.title.enResponsive micelles and vesicles based on polypeptide diblock copolymers
dc.typeArticle de revue
dc.identifier.doi10.1002/pat.821
dc.subject.halChimie/Polymères
bordeaux.journalPolymers for Advanced Technologies
bordeaux.page782-785
bordeaux.volume17
bordeaux.hal.laboratoriesLaboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629*
bordeaux.issue9-10
bordeaux.institutionBordeaux INP
bordeaux.institutionUniversité de Bordeaux
bordeaux.peerReviewedoui
hal.identifierhal-00396006
hal.version1
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00396006v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Polymers%20for%20Advanced%20Technologies&rft.date=2006&rft.volume=17&rft.issue=9-10&rft.spage=782-785&rft.epage=782-785&rft.eissn=1042-7147&rft.issn=1042-7147&rft.au=CH%C3%89COT,%20Fr%C3%A9d%C3%A9ric&RODRIGUEZ-HERNANDEZ,%20Juan&GNANOU,%20Yves&LECOMMANDOUX,%20Sebastien&rft.genre=article


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