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Impact of psychedelics on craving in addiction: A systematic review

dc.rights.licenseopenen_US
hal.structure.identifierSommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY]
dc.contributor.authorCHAPRON, Sophie-Athena
dc.contributor.authorBONAZZI, Guilhem
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorDI LODOVICO, Laura
dc.contributor.authorDE TERNAY, Julia
dc.contributor.authorLANDMANN, Camille
dc.contributor.authorNOURREDINE, Mikail
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorSALVO, Francesco
dc.contributor.authorSESSA, Ben
dc.contributor.authorDAS, Ravi
dc.contributor.authorROLLAND, Benjamin
dc.contributor.authorGARCIA-ROMEU, Albert
hal.structure.identifierSommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY]
dc.contributor.authorAURIACOMBE, Marc
dc.date.accessioned2025-04-15T12:54:49Z
dc.date.available2025-04-15T12:54:49Z
dc.date.issued2025-02-01
dc.identifier.issn1461-7285en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/206207
dc.description.abstractEnBACKGROUND: In the context of the need to increase treatment options for substance use disorders, recent research has evaluated the therapeutic potential of psychedelics. However, there is an incomplete understanding of psychedelics' effects on craving, a core symptom of addictive disorders and a predictor of substance use and relapse. AIMS: To determine if the use of psychedelics is associated with changes in craving in humans. METHODS: A systematic review of the literature, using PubMed, PsycInfo, and Scopus databases up to May 2023. We included all studies assessing any substance craving levels after psychedelic use (protocol registration number CRD42021242856). RESULTS: Thirty-eight published articles were included, corresponding to 31 studies and 2639 participants, pertaining either to alcohol, opioid, cocaine, or tobacco use disorders. Twelve of the 31 included studies reported a significant decrease in craving scores following psychedelic use. All but two studies had methodological issues, leading to moderate to high risk of bias scores. CONCLUSIONS: Some psychedelics may show promising anti-craving effects, yet the diversity and high risk of bias of extant studies indicate that these results are to be considered with caution. Further well-controlled and larger-scale trials should be encouraged.
dc.language.isoENen_US
dc.subject.enPsychedelics
dc.subject.enAddiction
dc.subject.enCraving
dc.subject.enHallucinogens
dc.subject.enSystematic Review
dc.subject.enUse Disorder
dc.title.enImpact of psychedelics on craving in addiction: A systematic review
dc.title.alternativeJ Psychopharmacolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1177/02698811241308613en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed39891564en_US
bordeaux.journalJournal of Psychopharmacologyen_US
bordeaux.page2698811241308613en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.institutionCNRS
bordeaux.teamAHEAD_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
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