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Systematic Aetiological Assessment of Myocarditis: A Prospective Cohort Study

dc.rights.licenseopenen_US
dc.contributor.authorMICHEL, Vincent
dc.contributor.authorLAZARO, Estibaliz
dc.contributor.authorFAUTHOUX, Thomas
dc.contributor.authorCETRAN, Laura
hal.structure.identifierImmunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle [ImmunoConcept]
dc.contributor.authorCONTIN-BORDES, Cécile
hal.structure.identifierImmunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle [ImmunoConcept]
dc.contributor.authorBLANCO, Patrick
dc.contributor.authorSEGUY, Benjamin
dc.contributor.authorBAUDINET, Thomas
dc.contributor.authorCOSTE, Pierre
dc.contributor.authorGERBAUD, Edouard
dc.date.accessioned2025-02-10T15:08:00Z
dc.date.available2025-02-10T15:08:00Z
dc.date.issued2024-02
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/204783
dc.description.abstractEnMyocarditis is commonly diagnosed in the intensive care cardiology unit (ICCU). No current recommendation nor guideline aids exist for aetiological assessments. Methods: From September 2021 to October 2023, 84 patients with acute myocarditis underwent thorough and systematic serum and blood cell panel evaluations to determine the most common causes of myocarditis. Results: Of the 84 patients (median age 34 years, range 22–41 years, 79% male), 16 presented with complicated myocarditis. The systematic aetiological assessment revealed that 36% of patients were positive for lupus anticoagulant, 12% for antinuclear antibodies, 8% for anti-heart antibodies, and 12% for anti-striated muscle antibodies. Viral serology did not yield any significant results. After the aetiological assessment, one patient was diagnosed with an autoimmune inflammatory disorder (Still’s disease). T-cell subset analyses indicated that myocarditis severity tended to increase with the T-cell lymphopenia status. Conclusions: A comprehensive, systematic aetiological assessment was of limited value in terms of predicting the clinical or therapeutic outcomes in myocarditis patients presenting to the ICCU.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enMyocarditis
dc.subject.enAutoimmune and inflammatory disorders
dc.subject.enAetiological assessment
dc.title.enSystematic Aetiological Assessment of Myocarditis: A Prospective Cohort Study
dc.typeArticle de revueen_US
dc.identifier.doi10.3390/jcm13041025en_US
dc.subject.halSciences du Vivant [q-bio]/Immunologieen_US
dc.identifier.pubmed38398340en_US
bordeaux.journalJournal of Clinical Medicineen_US
bordeaux.volume13en_US
bordeaux.hal.laboratoriesImmunoConcEpT - UMR 5164en_US
bordeaux.issue4en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-04938801
hal.version1
hal.date.transferred2025-02-10T15:08:03Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
dc.rights.ccCC BYen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20Clinical%20Medicine&rft.date=2024-02&rft.volume=13&rft.issue=4&rft.au=MICHEL,%20Vincent&LAZARO,%20Estibaliz&FAUTHOUX,%20Thomas&CETRAN,%20Laura&CONTIN-BORDES,%20C%C3%A9cile&rft.genre=article


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