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dc.rights.licenseopenen_US
dc.contributor.authorANTONIUSSEN, Christian S
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorPROUST LIMA, Cecile
ORCID: 0000-0002-9884-955X
IDREF: 114375747
dc.contributor.authorIBSEN, Daniel B
dc.contributor.authorOLSEN, Anja
dc.contributor.authorOVERVAD, Kim
dc.contributor.authorTJØNNELAND, Anne
dc.contributor.authorFERRARI, Pietro
dc.contributor.authorDAHM, Christina C
dc.date.accessioned2025-01-17T10:15:17Z
dc.date.available2025-01-17T10:15:17Z
dc.date.issued2024-12-01
dc.identifier.issn1573-7284en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/204358
dc.description.abstractEnAlcohol consumption is a risk factor for breast cancer (BC), yet little is known about longitudinal alcohol consumption patterns and risk of BC. This study aimed to investigate whether trajectory profiles of alcohol consumption across adulthood were associated with risk of first primary malignant BC in postmenopausal women. At baseline, 28,720 pre-and postmenopausal women aged 50-65 years from the Danish Diet, Cancer and Health Cohort reported their average alcohol intake over the past 12 months and their average alcohol intake at the ages of 20, 30, 40, and 50 years. Alcohol consumption trajectories were estimated using latent class mixed models. BC cases were identified through record linkage to the Danish Cancer Registry. To examine associations between alcohol consumption trajectories and BC, we fitted a proportional hazard model adjusted for potential confounding factors using data from 24,543 postmenopausal women without missing covariate information. We identified 4 alcohol consumption trajectory profiles. During a median follow-up of 16.5 years, 1,591 cases of BC occurred. A mean alcohol consumption trajectory of > 10 g/day was associated with higher risk of BC (HR: 1.65, 95%CI: 1.35-2.03) compared to a mean alcohol consumption trajectory of < 6 g/day. We found no association between trajectory profiles characterized by lower alcohol intakes in early adulthood followed by increasing consumption of alcohol in adulthood compared to a consistently low intake of alcohol. Postmenopausal women drinking consistently high amounts of alcohol throughout adulthood had a higher risk of BC compared to women with a consistently low intake of alcohol.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enHumans
dc.subject.enFemale
dc.subject.enBreast Neoplasms
dc.subject.enPostmenopause
dc.subject.enMiddle Aged
dc.subject.enDenmark
dc.subject.enAlcohol Drinking
dc.subject.enRisk Factors
dc.subject.enAged
dc.subject.enCohort Studies
dc.subject.enProportional Hazards Models
dc.subject.enAdult
dc.subject.enRegistries
dc.title.enAlcohol consumption trajectories and risk of breast cancer among postmenopausal women: a Danish cohort study.
dc.title.alternativeEur J Epidemiolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1007/s10654-024-01179-5en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed39630402en_US
bordeaux.journalEuropean Journal of Epidemiologyen_US
bordeaux.page1353-1362en_US
bordeaux.volume39en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue12en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamBIOSTAT_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDDanish Cancer Society Research Centeren_US
bordeaux.identifier.funderIDAarhus Universiteten_US
bordeaux.import.sourcepubmed
hal.identifierhal-04893377
hal.version1
hal.date.transferred2025-01-17T10:15:20Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&amp;rft_val_fmt=info:ofi/fmt:kev:mtx:journal&amp;rft.jtitle=European%20Journal%20of%20Epidemiology&amp;rft.date=2024-12-01&amp;rft.volume=39&amp;rft.issue=12&amp;rft.spage=1353-1362&amp;rft.epage=1353-1362&amp;rft.eissn=1573-7284&amp;rft.issn=1573-7284&amp;rft.au=ANTONIUSSEN,%20Christian%20S&amp;PROUST%20LIMA,%20Cecile&amp;IBSEN,%20Daniel%20B&amp;OLSEN,%20Anja&amp;OVERVAD,%20Kim&amp;rft.genre=article


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