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Reducing the prime cardiopulmonary bypass volume during paediatric cardiac surgery.

dc.rights.licenseopenen_US
dc.contributor.authorMATHIEU, Laurent
dc.contributor.authorBRUNETTI, César
dc.contributor.authorDETCHEPARE, Jean
dc.contributor.authorFLAMBARD, Maude
dc.contributor.authorGERMAIN, Christine
dc.contributor.authorLANGOUET, Elise
dc.contributor.authorTAFER, Nadir
dc.contributor.authorROUBERTIE, François
hal.structure.identifierBiologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases
dc.contributor.authorOUATTARA, Alexandre
dc.date.accessioned2024-12-09T10:41:37Z
dc.date.available2024-12-09T10:41:37Z
dc.date.issued2024-11-01
dc.identifier.issn1477-111Xen_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/203791
dc.description.abstractEnDespite technological advances, the use of homologous blood to prime the cardiopulmonary bypass (CPB) circuits of infants under 10 kg remains common. However, such rapid massive transfusion may increase post-CPB morbidity. We retrospectively included consecutive patients weighing 2.3-10 kg who underwent cardiac surgery under CPB. Patients were divided into two groups based on their priming volumes: low priming volume (LPV) (below the median volume) or high priming volume (HPV) (the median volume or above). The study included 208 patients, of whom 104 had priming volumes below the median [37.9 (28.4-51.7) mL/kg] and 104 had at least the median volume. We recorded positive correlations between the priming volume, on the one hand, and the peak creatinine and CRP levels within 5 days postoperatively, the duration of intensive care unit (ICU) stay, and the mechanical ventilation time, on the other. A relationship was also observed between a higher median priming volume and the need for renal replacement therapy in the ICU and mediastinitis. Although the differences in priming volume between the twogroups were small, they significantly influenced the postoperative complications. Perfusionists should seek to limit the priming volume to reduce the post-CPB inflammatory response, the duration of ICU stay, and possibly the risk of mediastinitis.
dc.language.isoENen_US
dc.subject.enblood transfusion; cardiac surgical procedures; congenital heart defects; mediastinitis; paediatrics; perfusionists.
dc.title.enReducing the prime cardiopulmonary bypass volume during paediatric cardiac surgery.
dc.title.alternativePerfusionen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1177/02676591241296319en_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologieen_US
dc.identifier.pubmed39484829en_US
bordeaux.journalPerfusionen_US
bordeaux.page2676591241296319en_US
bordeaux.hal.laboratoriesBiologie des maladies cardiovasculaires (BMC) - UMR 1034en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.identifierhal-04826619
hal.version1
hal.date.transferred2024-12-09T10:41:39Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Perfusion&rft.date=2024-11-01&rft.spage=2676591241296319&rft.epage=2676591241296319&rft.eissn=1477-111X&rft.issn=1477-111X&rft.au=MATHIEU,%20Laurent&BRUNETTI,%20C%C3%A9sar&DETCHEPARE,%20Jean&FLAMBARD,%20Maude&GERMAIN,%20Christine&rft.genre=article


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